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TargetMol | Compound Library

Anti-Fibrosis Compound Library

Catalog No. L9810

Fibrosis, also known as fibrotic scarring, is a pathological wound healing in which connective tissue replaces normal parenchymal tissue to the extent that it goes unchecked, leading to considerable tissue remodeling and the formation of permanent scar tissue. If highly progressive, the fibrotic process eventually leads to organ malfunction and death. Fibrosis affects nearly every tissue in the body, such as lung, liver, kidney, bone marrow, etc. Fibrosis is the final, common pathological outcome of many chronic inflammatory diseases, including scleroderma, rheumatoid arthritis, Crohn's disease, ulcerative colitis, myelofibrosis and systemic lupus erythematosus.

TargetMol's Anti-Fibrosis Compound Library collects 1800 potential anti-fibrosis compounds, including inhibitors to TGF-beta, TNF-alpha, MMP, etc., antioxidants, anti-inflammatory compounds, etc. It is a powerful tool for research in fibrosis and related drug development.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L9810

Anti-Fibrosis Compound Library

size

  • 1 mg
  • 10 µL x 10 mM (in DMSO)
  • 20 µL x 10 mM (in DMSO)
  • 30 µL x 10 mM (in DMSO)
  • 50 µL x 10 mM (in DMSO)
  • 100 µL x 10 mM (in DMSO)
  • 250 µL x 10 mM (in DMSO)
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Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

Product features Product features

  • A unique collection of 1800 potential anti-fibrosis compounds, can be used in HTS and HCS;
  • Targets include TGFβ、TNFα、MMP、EGFR、NADPH-oxidase, etc.
  • Some compounds are in the market (FDA-approved);
  • Detailed compound information with structure, target, IC50, and biological activity description;
  • NMR and HPLC/LCMS validated to ensure high purity and quality.

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Apoptosis
Autophagy
NF-κB
PI3K
ROS
Reactive Oxygen Species
COX
Endogenous Metabolite
VEGFR
Ras
p38 MAPK
Antibacterial
ERK
Akt
PDGFR
MMP
mTOR
Wnt/beta-catenin
TNF
Antioxidant
AMPK
TGF-beta/Smad
Raf
GSK-3
JNK
CDK
c-Kit
FGFR
MEK
FLT
Parasite
Interleukin
IκB/IKK
Caspase
NO Synthase
Src
EGFR
MAPK
DNA-PK
IL Receptor
DNA/RNA Synthesis
STAT
Antibiotic
CFTR
Ferroptosis
S6 Kinase
ATM/ATR
HIV Protease
ALK
Kras
Antifungal
Mitophagy
PPAR
Calcium Channel
JAK
Nrf2
NOD
RIP kinase
Bcl-2 Family
Influenza Virus
Bcr-Abl
Cytochromes P450
Hedgehog/Smoothened
NOD-like Receptor (NLR)
PDK
c-Met/HGFR
PKC
Aurora Kinase
c-RET
IRAK
Virus Protease
PDE
Mitochondrial Metabolism
HIF/HIF Prolyl-Hydroxylase
PKA
Lipoxygenase
IGF-1R
Casein Kinase
Beta Amyloid
Potassium Channel
NOS
c-Fms
Dehydrogenase
Phosphatase
Rho
HSV
Cholinesterase (ChE)
SARS-CoV
Tyrosine Kinases
P-gp
Prostaglandin Receptor
Tyrosinase
FAK
MLK
ROCK
Topoisomerase
TLR
PI4K
Sodium Channel
Drug Metabolite
Trk receptor
AChR
Tie-2
PARP
TRP/TRPV Channel
Glucosidase
Smo
PTEN
PGE Synthase
HSP
HDAC
GABA Receptor
Syk
Anti-infection
p53
Proteasome
Integrin
LPL Receptor
Glutathione Peroxidase
Estrogen Receptor/ERR
Serine Protease
Adrenergic Receptor
Chk
Epigenetic Reader Domain
ATPase
Chloride channel
HCV Protease
Adenosine Receptor
Reductase
BACE
NADPH
RANKL/RANK
E1/E2/E3 Enzyme
Gamma-secretase
Antifection
Angiotensin-converting Enzyme (ACE)
CaMK
MNK
Antiviral
Phospholipase
MDM-2/p53
HER
GPCR
Carbonic Anhydrase
Transferase
Estrogen/progestogen Receptor
PERK
Necroptosis
TOPK
Serine/threonin kinase
Immunology/Inflammation related
CSF-1R
IAP
SIK
UGT
BTK
Opioid Receptor
Ligands for E3 Ligase
glycosidase
OXPHOS
Porcupine
Free radical scavengers
Ephrin Receptor
transporter
ASK
Pyroptosis
ribosome
LPA Receptor
5-HT Receptor
PLK
TAM Receptor
Microtubule Associated
ROS Kinase
PD-1/PD-L1
Monoamine Oxidase
S1P Receptor
RAAS
GTPase
c-Myc
MRP
HBV
Cysteine Protease
Leukotriene Receptor
FXR
Aryl Hydrocarbon Receptor
Molecular Glues
CCR
Lipid
Beta-Secretase
Survivin
LRRK2
Aminopeptidase
Histone Acetyltransferase
Retinoid Receptor
KLF
HIF
SGK
Cannabinoid Receptor
NADPH-oxidase
Mdm2
Proton pump
Histone Methyltransferase
MyD88
LTR
DYRK
Histamine Receptor
Liver X Receptor
PYK2
MAO
Glucocorticoid Receptor
Prolyl Endopeptidase (PREP)
IRE1
Adenylate cyclase
LDL
DNA gyrase
Fatty Acid Synthase
DNA Alkylation
PAK
GluR
SGLT
ATP Citrate Lyase
PAI-1
MELK
Hippo pathway
FKBP
Gap Junction Protein
AhR
IKZF
PROTACs
GSNOR
NPC1L1
Monocarboxylate transporter
RAR/RXR
CD38
DHFR
Dopamine Receptor
ROR
Dynamin
Y Box Binding Protein 1
YAP
Arginase
IFNAR
Histone Demethylase
gp120/CD4
Galectin
N-Acetylglucosaminyltransferase
Cholecystokinin Receptor
AAK1
Photosensitizer
Hck
Cell Cycle Arrest
Amylase
IDO
iGluR
Myosin
Haspin Kinase
P2X Receptor
ABC Transporter
Anion Exchanger
Guanylate cyclase
FAAH
Stearoyl-CoA Desaturase (SCD)
ACK1
CXCR
Somatostatin
PAD
cAMP
DNA
DUB
Androgen Receptor
Indoleamine 2,3-Dioxygenase (IDO)
BCRP
Glutathione reductase
Acyltransferase
STING
GPCR19
Sirtuin
AIM2
CD74
Decarboxylase
cGAS
RSV
Methionine Adenosyltransferase (MAT)
GST
GPX
Reverse Transcriptase
FOXO3
Aromatase
Hydroxylase
Adenosine Deaminase
Cuproptosis
Discoidin Domain Receptor (DDR)
Platelet aggregation
BMI-1
Tight Junction Protein
Thrombin
Kinesin
PKM
ADC Cytotoxin
FOXO

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