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TargetMol | Compound Library

Anti-Fibrosis Compound Library

Catalog No. L9810

Fibrosis, also known as fibrotic scarring, is a pathological wound healing in which connective tissue replaces normal parenchymal tissue to the extent that it goes unchecked, leading to considerable tissue remodeling and the formation of permanent scar tissue. If highly progressive, the fibrotic process eventually leads to organ malfunction and death. Fibrosis affects nearly every tissue in the body, such as lung, liver, kidney, bone marrow, etc. Fibrosis is the final, common pathological outcome of many chronic inflammatory diseases, including scleroderma, rheumatoid arthritis, Crohn’s disease, ulcerative colitis, myelofibrosis and systemic lupus erythematosus. TargetMol’s Anti-Fibrosis Compound Library collects 1800 potential anti-fibrosis compounds, including inhibitors to TGF-beta, TNF-alpha, MMP, etc., antioxidants, anti-inflammatory compounds, etc. It is a powerful tool for research in fibrosis and related drug development.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L9810

Anti-Fibrosis Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product features Product features

  • A unique collection of 1800 potential anti-fibrosis compounds, can be used in HTS and HCS;
  • Targets include TGFβ、TNFα、MMP、EGFR、NADPH-oxidase, etc.
  • Some compounds are in the market (FDA-approved);
  • Detailed compound information with structure, target, IC50, and biological activity description;
  • NMR and HPLC/LCMS validated to ensure high purity and quality.

Packaging And Storage | TargetMol Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

Library Customization | TargetMol Library Customization

Compound Library | TargetMol
Targetmol Compound Libraries
can be highly customized!
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Library Customization | TargetMol Library Composition

Apoptosis
Autophagy
PI3K
VEGFR
PDGFR
COX
mTOR
Raf
Wnt/beta-catenin
c-Kit
Reactive Oxygen Species
MMP
TGF-beta/Smad
GSK-3
CDK
NF-κB
FGFR
p38 MAPK
FLT
Ras
ERK
Akt
AMPK
Src
MEK
IκB/IKK
DNA-PK
CFTR
MAPK
TNF
JNK
EGFR
ALK
ATM/ATR
S6 Kinase
Kras
RIP kinase
JAK
Bcr-Abl
Aurora Kinase
Antibacterial
Hedgehog/Smoothened
c-RET
Antibiotic
c-Met/HGFR
Antioxidant
PDK
Ferroptosis
Mitophagy
Rho
PKC
Endogenous Metabolite
IRAK
PKA
Tyrosine Kinases
Parasite
PDE
IL Receptor
c-Fms
NOD
Calcium Channel
ROCK
Casein Kinase
NOD-like Receptor (NLR)
Mitochondrial Metabolism
IGF-1R
Interleukin
Trk receptor
PI4K
Potassium Channel
MLK
Influenza Virus
ROS
Chk
DNA/RNA Synthesis
STAT
FAK
HER
Dehydrogenase
Antifungal
PPAR
Serine Protease
SIK
MNK
Nrf2
Syk
HIV Protease
NADPH
Tie-2
Glutathione Peroxidase
TOPK
Virus Protease
CSF-1R
E1/E2/E3 Enzyme
Drug Metabolite
BTK
Smo
Lipoxygenase
Epigenetic Reader Domain
Porcupine
Free radical scavengers
Ephrin Receptor
ASK
Ligand for E3 Ligase
LPA Receptor
ribosome
AChR
TAM Receptor
Proteasome
Chloride channel
ATPase
LPL Receptor
RAAS
Phosphatase
c-Myc
Caspase
TRP/TRPV Channel
Adrenergic Receptor
Molecular Glues
BCL
PGE Synthase
Antiviral
HSP
Prostaglandin Receptor
SARS-CoV
LRRK2
KLF
GPR
P450
PLK
SGK
p53
Monoamine Oxidase
S1P Receptor
Carbonic Anhydrase
Transferase
Histone Methyltransferase
HCV Protease
Integrin
Estrogen/progestogen Receptor
LTR
Adenosine Receptor
BACE
GTPase
MRP
Serine/threonin kinase
Cysteine Protease
Glucocorticoid Receptor
Immunology/Inflammation related
Topoisomerase
IRE1
DNA gyrase
DNA Alkylation
HSV
CCR
PTEN
ACK
Lipid
MELK
HDAC
Phospholipase
Gap Junction Protein
Sodium Channel
Mdm2
Proton pump
Adenylyl cyclase
PROTACs
NOS
GSNOR
Monocarboxylate transporter
YAP
Reductase
IFNAR
DYRK
Histone Demethylase
Histamine Receptor
Galectin
ABC
N-Acetylglucosaminyltransferase
Estrogen Receptor/ERR
Hck
Leukotriene Receptor
FXR
PYK2
MAO
Aryl Hydrocarbon Receptor
IAP
Myosin
UGT
Haspin Kinase
Gamma-secretase
LDL
AAK1 (AP2 associated kinase 1)
P2X Receptor
Anion Exchanger
Guanylate cyclase
Fatty Acid Synthase
FAAH
Somatostatin
cAMP
CaMK
DNA
DUB
Indoleamine 2,3-Dioxygenase (IDO)
SGLT
ATP Citrate Lyase
OXPHOS
Beta-Secretase
AChE
P-gp
Acyltransferase
STING
Aminopeptidase
Histone Acetyltransferase
cGAS
PAI-1
Methionine Adenosyltransferase (MAT)
Hippo pathway
GST
Beta Amyloid
GPX
Retinoid Receptor
CRISPR/Cas9
Hydroxylase
Adenosine deaminase
Discoidin Domain Receptor (DDR)
NADPH-oxidase
BMI-1
cholecystokinin
Tyrosinase
Microtubule Associated
Thrombin
PD-1/PD-L1
NO Synthase

Keywords