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TargetMol | Compound Library

Anti-Fibrosis Compound Library

Catalog No. L9810

Fibrosis, also known as fibrotic scarring, is a pathological wound healing in which connective tissue replaces normal parenchymal tissue to the extent that it goes unchecked, leading to considerable tissue remodeling and the formation of permanent scar tissue. If highly progressive, the fibrotic process eventually leads to organ malfunction and death. Fibrosis affects nearly every tissue in the body, such as lung, liver, kidney, bone marrow, etc. Fibrosis is the final, common pathological outcome of many chronic inflammatory diseases, including scleroderma, rheumatoid arthritis, Crohn's disease, ulcerative colitis, myelofibrosis and systemic lupus erythematosus.

TargetMol's Anti-Fibrosis Compound Library collects 1800 potential anti-fibrosis compounds, including inhibitors to TGF-beta, TNF-alpha, MMP, etc., antioxidants, anti-inflammatory compounds, etc. It is a powerful tool for research in fibrosis and related drug development.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L9810

Anti-Fibrosis Compound Library

sizeIn stock

  • 1 mg
  • 10 µL x 10 mM (in DMSO)
  • 20 µL x 10 mM (in DMSO)
  • 30 µL x 10 mM (in DMSO)
  • 50 µL x 10 mM (in DMSO)
  • 100 µL x 10 mM (in DMSO)
  • 250 µL x 10 mM (in DMSO)
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Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

Product features Product features

  • A unique collection of 1800 potential anti-fibrosis compounds, can be used in HTS and HCS;
  • Targets include TGFβ、TNFα、MMP、EGFR、NADPH-oxidase, etc.
  • Some compounds are in the market (FDA-approved);
  • Detailed compound information with structure, target, IC50, and biological activity description;
  • NMR and HPLC/LCMS validated to ensure high purity and quality.

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Apoptosis
Autophagy
NF-κB
PI3K
ROS
Reactive Oxygen Species
COX
Endogenous Metabolite
VEGFR
Ras
p38 MAPK
Antibacterial
ERK
Akt
PDGFR
MMP
mTOR
Wnt/beta-catenin
Antioxidant
TNF
AMPK
TGF-beta/Smad
Raf
GSK-3
JNK
CDK
c-Kit
FGFR
MEK
FLT
Parasite
Interleukin
IκB/IKK
Caspase
NO Synthase
Src
MAPK
EGFR
DNA-PK
IL Receptor
DNA/RNA Synthesis
STAT
Antibiotic
CFTR
S6 Kinase
Ferroptosis
ATM/ATR
HIV Protease
Kras
ALK
Mitophagy
Calcium Channel
JAK
Antifungal
PPAR
NOD
Nrf2
Bcl-2 Family
RIP kinase
Influenza Virus
Bcr-Abl
Cytochromes P450
Hedgehog/Smoothened
NOD-like Receptor (NLR)
PDK
c-Met/HGFR
Aurora Kinase
PKC
c-RET
IRAK
Virus Protease
Mitochondrial Metabolism
HIF/HIF Prolyl-Hydroxylase
PDE
PKA
IGF-1R
Casein Kinase
Potassium Channel
Lipoxygenase
Beta Amyloid
c-Fms
Dehydrogenase
NOS
SARS-CoV
HSV
Cholinesterase (ChE)
Rho
Phosphatase
Tyrosine Kinases
FAK
P-gp
Prostaglandin Receptor
Tyrosinase
MLK
PI4K
Sodium Channel
ROCK
Topoisomerase
TLR
AChR
Trk receptor
Drug Metabolite
Tie-2
Glucosidase
Smo
HSP
HDAC
Syk
PARP
GABA Receptor
PGE Synthase
TRP/TRPV Channel
Anti-infection
PTEN
p53
Proteasome
Integrin
Estrogen Receptor/ERR
Epigenetic Reader Domain
Serine Protease
Chk
LPL Receptor
Adrenergic Receptor
Glutathione Peroxidase
Reductase
Phospholipase
ATPase
E1/E2/E3 Enzyme
HER
Gamma-secretase
Angiotensin-converting Enzyme (ACE)
MNK
Adenosine Receptor
MDM-2/p53
Antifection
BACE
NADPH
RANKL/RANK
CaMK
Antiviral
Chloride channel
HCV Protease
TOPK
CSF-1R
SIK
TAM Receptor
Carbonic Anhydrase
PERK
IAP
glycosidase
Porcupine
ribosome
Immunology/Inflammation related
PLK
S1P Receptor
GPCR
Ephrin Receptor
ROS Kinase
PD-1/PD-L1
Estrogen/progestogen Receptor
UGT
Ligands for E3 Ligase
ASK
Microtubule Associated
Transferase
Necroptosis
transporter
LPA Receptor
5-HT Receptor
Monoamine Oxidase
Serine/threonin kinase
Opioid Receptor
OXPHOS
Free radical scavengers
Pyroptosis
RAAS
Beta-Secretase
HBV
CCR
KLF
GTPase
c-Myc
Histone Acetyltransferase
HIF
MRP
Survivin
Aminopeptidase
Molecular Glues
Lipid
SGK
Cysteine Protease
Leukotriene Receptor
FXR
Aryl Hydrocarbon Receptor
LRRK2
Retinoid Receptor
Cannabinoid Receptor
NADPH-oxidase
Histamine Receptor
DNA Alkylation
LTR
GluR
ATP Citrate Lyase
Hippo pathway
Mdm2
DYRK
Liver X Receptor
MAO
PAK
PAI-1
MELK
Gap Junction Protein
Histone Methyltransferase
PYK2
Adenylate cyclase
Fatty Acid Synthase
Glucocorticoid Receptor
SGLT
AhR
Proton pump
MyD88
Prolyl Endopeptidase (PREP)
IRE1
LDL
DNA gyrase
FKBP
IKZF
BTK
NPC1L1
DHFR
Cholecystokinin Receptor
AAK1
Myosin
Glutathione reductase
Acyltransferase
Decarboxylase
Adenosine Deaminase
PROTACs
CD38
Histone Demethylase
N-Acetylglucosaminyltransferase
iGluR
ABC Transporter
Anion Exchanger
FAAH
DNA
Sirtuin
CD74
cGAS
Hydroxylase
ROR
Dynamin
Galectin
Cell Cycle Arrest
Haspin Kinase
DUB
GPCR19
RSV
Tight Junction Protein
GSNOR
Y Box Binding Protein 1
Arginase
gp120/CD4
Photosensitizer
cAMP
AIM2
GST
Reverse Transcriptase
Aromatase
Platelet aggregation
Dopamine Receptor
P2X Receptor
Somatostatin
PAD
Indoleamine 2,3-Dioxygenase (IDO)
Androgen Receptor
BCRP
Methionine Adenosyltransferase (MAT)
Cuproptosis
Discoidin Domain Receptor (DDR)
Kinesin
YAP
IFNAR
Hck
IDO
Na-K-Cl cotransporter
Stearoyl-CoA Desaturase (SCD)
ACK1
FOXO3
BMI-1
Thrombin
Monocarboxylate transporter
RAR/RXR
Amylase
Guanylate cyclase
CXCR
STING
GPX
PKM
ADC Cytotoxin
FOXO

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