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TargetMol | Compound Library

Anti-Fibrosis Compound Library

Catalog No. L9810

Fibrosis, also known as fibrotic scarring, is a pathological wound healing in which connective tissue replaces normal parenchymal tissue to the extent that it goes unchecked, leading to considerable tissue remodeling and the formation of permanent scar tissue. If highly progressive, the fibrotic process eventually leads to organ malfunction and death. Fibrosis affects nearly every tissue in the body, such as lung, liver, kidney, bone marrow, etc. Fibrosis is the final, common pathological outcome of many chronic inflammatory diseases, including scleroderma, rheumatoid arthritis, Crohn's disease, ulcerative colitis, myelofibrosis and systemic lupus erythematosus.

TargetMol's Anti-Fibrosis Compound Library collects 1800 potential anti-fibrosis compounds, including inhibitors to TGF-beta, TNF-alpha, MMP, etc., antioxidants, anti-inflammatory compounds, etc. It is a powerful tool for research in fibrosis and related drug development.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L9810

Anti-Fibrosis Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

Product features Product features

  • A unique collection of 1800 potential anti-fibrosis compounds, can be used in HTS and HCS;
  • Targets include TGFβ、TNFα、MMP、EGFR、NADPH-oxidase, etc.
  • Some compounds are in the market (FDA-approved);
  • Detailed compound information with structure, target, IC50, and biological activity description;
  • NMR and HPLC/LCMS validated to ensure high purity and quality.

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Apoptosis
Autophagy
NF-κB
PI3K
ROS
Reactive Oxygen Species
COX
Endogenous Metabolite
Ras
VEGFR
p38 MAPK
Antibacterial
ERK
Akt
PDGFR
MMP
mTOR
Wnt/beta-catenin
TNF
Antioxidant
AMPK
TGF-beta/Smad
Raf
GSK-3
JNK
c-Kit
CDK
FGFR
MEK
FLT
Parasite
IκB/IKK
Interleukin
NO Synthase
Caspase
Src
MAPK
DNA/RNA Synthesis
DNA-PK
IL Receptor
STAT
Antibiotic
EGFR
CFTR
S6 Kinase
Ferroptosis
ATM/ATR
ALK
Calcium Channel
Kras
HIV Protease
Antifungal
PPAR
RIP kinase
Mitophagy
Bcl-2 Family
JAK
Nrf2
Influenza Virus
Bcr-Abl
Cytochromes P450
NOD
Hedgehog/Smoothened
PDK
NOD-like Receptor (NLR)
Aurora Kinase
PKC
c-Met/HGFR
Mitochondrial Metabolism
c-RET
Lipoxygenase
IRAK
PDE
HIF/HIF Prolyl-Hydroxylase
Virus Protease
Casein Kinase
Potassium Channel
IGF-1R
PKA
NOS
c-Fms
Beta Amyloid
Prostaglandin Receptor
Rho
SARS-CoV
HSV
Dehydrogenase
Phosphatase
Tyrosine Kinases
Cholinesterase (ChE)
P-gp
FAK
MLK
Tyrosinase
PI4K
ROCK
TLR
Trk receptor
Drug Metabolite
Topoisomerase
PARP
AChR
Sodium Channel
p53
Tie-2
HDAC
HSP
GABA Receptor
Epigenetic Reader Domain
Syk
PTEN
Glucosidase
Smo
PGE Synthase
Proteasome
Serine Protease
TRP/TRPV Channel
LPL Receptor
Anti-infection
Integrin
NADPH
Adrenergic Receptor
Glutathione Peroxidase
Estrogen Receptor/ERR
Chk
ATPase
Adenosine Receptor
c-Myc
Antiviral
Gamma-secretase
Reductase
transporter
Antifection
CaMK
Phospholipase
HCV Protease
MNK
RANKL/RANK
MDM-2/p53
E1/E2/E3 Enzyme
PERK
BACE
Chloride channel
Monoamine Oxidase
Angiotensin-converting Enzyme (ACE)
PLK
TAM Receptor
Pyroptosis
Porcupine
IAP
Ligand for E3 Ligase
glycosidase
S1P Receptor
Free radical scavengers
ROS Kinase
Carbonic Anhydrase
ASK
RAAS
Estrogen/progestogen Receptor
TOPK
CSF-1R
5-HT Receptor
Microtubule Associated
LPA Receptor
Serine/threonin kinase
Immunology/Inflammation related
Transferase
HER
Necroptosis
OXPHOS
GPCR
UGT
SIK
Ephrin Receptor
ribosome
Opioid Receptor
PD-1/PD-L1
NADPH-oxidase
Cannabinoid Receptor
Leukotriene Receptor
LDL
MRP
HIF
Cysteine Protease
Survivin
Retinoid Receptor
FXR
GTPase
Beta-Secretase
Molecular Glues
Histone Acetyltransferase
CCR
SGK
HBV
KLF
Lipid
Aryl Hydrocarbon Receptor
LRRK2
IRE1
Glucocorticoid Receptor
MyD88
FKBP
Histamine Receptor
Mdm2
DYRK
PYK2
Prolyl Endopeptidase (PREP)
Hippo pathway
MELK
SGLT
Aminopeptidase
ATP Citrate Lyase
Proton pump
Liver X Receptor
MAO
DNA Alkylation
Sirtuin
PAI-1
DNA gyrase
Histone Methyltransferase
LTR
AhR
Fatty Acid Synthase
Gap Junction Protein
Myosin
PAK
FOXO3
IKZF
BTK
Somatostatin
DUB
GSNOR
RAR/RXR
YAP
PKM
RSV
Histone Demethylase
CD38
Cholecystokinin Receptor
BCRP
ROR
Haspin Kinase
CXCR
CD74
Aromatase
Glutathione reductase
Decarboxylase
BMI-1
cGAS
Amylase
Adenosine Deaminase
Platelet aggregation
AAK1
DHFR
NPC1L1
Anion Exchanger
Cuproptosis
P2X Receptor
Discoidin Domain Receptor (DDR)
CRISPR/Cas9
Monocarboxylate transporter
Guanylate cyclase
GPCR19
GluR
N-Acetylglucosaminyltransferase
Methionine Adenosyltransferase (MAT)
Stearoyl-CoA Desaturase (SCD)
IDO
Indoleamine 2,3-Dioxygenase (IDO)
ACK1
Dopamine Receptor
iGluR
FAAH
DNA
Androgen Receptor
Arginase
GST
Dynamin
AIM2
Y Box Binding Protein 1
Hydroxylase
cAMP
Cell Cycle Arrest
Na-K-Cl cotransporter
Kinesin
gp120/CD4
Galectin
GPX
Photosensitizer
Adenylyl Cyclase
Reverse Transcriptase
IFNAR
Acyltransferase
Thrombin
Tight Junction Protein
STING
Hck
PROTACs
PAD
ABC Transporter
ADC Cytotoxin

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