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TargetMol | Compound Library

RO5 Drug-like Natural Product Library

Catalog No. L6160

Natural products are important sources of lead compounds and drug candidates. They have complex scaffold structures and rich functional groups. Their structures are unique, and most of them are chiral. These naturally occurring advantages provide more diverse options for the transformation of natural products into drugs, and are also the reasons why natural products play an important role in drug development and research.
Based on the structural diversity and novelty of natural products, TargetMol used the druglikeness prediction index "Lipinski's Rule of Five" to select 2534 natural product monomers with good druggabilities, covering diverse structures from vast sources such as terpenes and alkaloids. The library is consisted of monomers with both biological activity and drug-like properties. It is a powerful tool for subsequent structure-effect optimization and innovative drug research.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L6160

RO5 Drug-like Natural Product Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • 2534 is a collection of natural products that meet the "Lipinski's Rule of Five" and have high potential for drug discovery.
  • Most of the NPs have clear biological activities, with various functions including anti-tumor, anti-inflammatory, antioxidant, neuroprotection and more.
  • Structural diversity, containing flavonoids, saponins, terpenoids, alkaloids and other categories.
  • Various detection techniques such as NMR, HPLC/LCMS to ensure accurate structure and high purity of the products and reduce false positives.

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Endogenous Metabolite
Apoptosis
Antibacterial
NF-κB
Autophagy
ROS
Antifungal
Parasite
COX
Reactive Oxygen Species
Akt
Antibiotic
p38 MAPK
Cytochromes P450
Antioxidant
Caspase
Interleukin
TNF
ERK
PI3K
NO Synthase
DNA/RNA Synthesis
Influenza Virus
Nrf2
STAT
GABA Receptor
Calcium Channel
AChR
Anti-infection
JNK
Bcl-2 Family
Virus Protease
Tyrosinase
Ferroptosis
MMP
PPAR
Cholinesterase (ChE)
Drug Metabolite
AMPK
IL Receptor
HIV Protease
Estrogen Receptor/ERR
Dehydrogenase
TRP/TRPV Channel
PARP
Lipoxygenase
Estrogen/progestogen Receptor
Glucosidase
HSV
glycosidase
Antifection
5-HT Receptor
Adrenergic Receptor
Mitochondrial Metabolism
Microtubule Associated
Amino Acids and Derivatives
Wnt/beta-catenin
Nucleoside Antimetabolite/Analog
PKC
iGluR
CDK
Potassium Channel
PDE
NOS
JAK
TGF-beta/Smad
P-gp
mTOR
SARS-CoV
TLR
Beta Amyloid
VEGFR
EGFR
NOD-like Receptor (NLR)
Phosphatase
Mitophagy
Immunology/Inflammation related
Topoisomerase
Prostaglandin Receptor
HDAC
ATPase
NMDAR
Sodium Channel
HIF/HIF Prolyl-Hydroxylase
Monoamine Oxidase
Dopamine Receptor
PKA
MAO
Phospholipase
GSK-3
Antiviral
PERK
Aryl Hydrocarbon Receptor
GluR
Sirtuin
GPCR
Chloride channel
Adenosine Receptor
Glucocorticoid Receptor
Androgen Receptor
HSP
IκB/IKK
Ras
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Histamine Receptor
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FXR
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Opioid Receptor
MDM-2/p53
HBV
CaMK
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transporter
HCV Protease
Serine Protease
Gamma-secretase
IGF-1R
Pyroptosis
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Platelet aggregation
NOD
p53
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ATG
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IAP
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HIF
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DNA Methyltransferase
FAK
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Imidazoline Receptor
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gp120/CD4
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Leukotriene Receptor
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cAMP
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OXPHOS
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MyD88
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LPL Receptor
P2Y Receptor
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OCT
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ASCT
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Glucokinase
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MT Receptor
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Na-K-Cl cotransporter
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STING
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