CCL21 Protein, Human, Recombinant

Name: CCL21 Protein, Human, Recombinant
Brand: TargetMol
SKU: TMPY-02244
Price: 112 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: TCA4, SLC, SCYA21, RP11-195F19.22-001, MGC34555, ECL, CKb9, chemokine (C-C motif) ligand 21, 6Ckine) Copy Product Info

Synonyms: TCA4, SLC, SCYA21, RP11-195F19.22-001, MGC34555, ECL, CKb9, chemokine (C-C motif) ligand 21, 6Ckine

Catalog No. TMPY-02244 Copy Product Info

CCL21 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 12.3 kDa and the accession number is O00585.

Pack Size	Price	USA Stock	Global Stock
5 µg	$112	-	In Stock
10 µg	$188	-	In Stock
20 µg	$297	7-10 days	7-10 days
50 µg	$618	7-10 days	7-10 days
100 µg	$939	7-10 days	7-10 days
200 µg	$1,470	7-10 days	7-10 days
500 µg	$2,560	7-10 days	7-10 days
1 mg	$4,660	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Measured by its binding ability in a functional ELISA. Immobilized human CCL21 at 2 μg/ml (100 μl/well) can bind human IGFBP7 with a linear range of 0.16-4 μg/ml.
Description	CCL21 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 12.3 kDa and the accession number is O00585.
Species	Human
Expression System	Baculovirus Insect Cells
Tag	Tag Free
Accession Number	O00585
Construction	A DNA sequence encoding the human CCL21 (O00585) (Met 1-Pro 134) was expressed and purified. Predicted N terminal: Ser 24
Protein Purity	> 98 % as determined by SDS-PAGE
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing 40 mM Tris, 0.3 M NaCl, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Synonyms	TCA4, SLC, SCYA21, RP11-195F19.22-001, MGC34555, ECL, CKb9, chemokine (C-C motif) ligand 21, 6Ckine
Research Background	Chemokines are a family of small chemotactic cytokines, or proteins secreted by cells. Chemokines share the same structure similarities such as small size, and the presence of four cysteine residues in conserved locations in order to form their 3-dimensional shape. Some of the chemokines are considered pro-inflammatory which can be induced to recruit cells of the immune system to a site of infection during an immune response, while others are considered homeostatic and are implied in controlling the migration of cells during normal processes of tissue maintenance and development. There are four members of the chemokine family: C-C kemokines, C kemokines, CXC kemokines and CX3C kemokines. The C-C kemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands-1 to 28. Chemokine ligand 21(CCL21), also known as 6Ckine, exodus-2, and secondary lymphoid-tissue chemokine(SLC), is a small cytokine belonging to the C-C chemokine family. CCL21 takes its name 6Ckine for its consititutively six conserved cysteine residues but not four cysteines typical to chemokines. CCL21 has function in ininducing vigorous calcium migrations and chemotactic responses.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy

Chemical Properties

Molecular Weight

12.3 kDa (predicted); 18 kDa (reducing conditions)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.