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Anti-HAS2 Antibody (1J651)

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Catalog No. TMAB-06891

Anti-HAS2 Antibody (1J651) is a Mouse antibody targeting HAS2. Anti-HAS2 Antibody (1J651) can be used in WB.

Anti-HAS2 Antibody (1J651)

Anti-HAS2 Antibody (1J651)

😃Good
Catalog No. TMAB-06891
Anti-HAS2 Antibody (1J651) is a Mouse antibody targeting HAS2. Anti-HAS2 Antibody (1J651) can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2207-10 days7-10 days
100 μL$3727-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-HAS2 Antibody (1J651) is a Mouse antibody targeting HAS2. Anti-HAS2 Antibody (1J651) can be used in WB.
Ig Type
IgG1, k
Clone
1J651
Reactivity
Human
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Monoclonal
Host SpeciesMouse
Subcellular LocalizationMembrane.
Tissue SpecificityExpressed in fibroblasts.
ConstructionHybridoma Monoclonal Antibody
PurificationProtein G purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundHyaluronan or hyaluronic acid (HA) is a high molecular weight unbranched polysaccharide synthesized by a wide variety of organisms from bacteria to mammals, and is a constituent of the extracellular matrix. It consists of alternating glucuronic acid and N-acetylglucosamine residues that are linked by beta-1-3 and beta-1-4 glycosidic bonds. HA is synthesized by membrane-bound synthase at the inner surface of the plasma membrane, and the chains are extruded through pore-like structures into the extracellular space. It serves a variety of functions, including space filling, lubrication of joints, and provision of a matrix through which cells can migrate. HA is actively produced during wound healing and tissue repair to provide a framework for ingrowth of blood vessels and fibroblasts. Changes in the serum concentration of HA are associated with inflammatory and degenerative arthropathies such as rheumatoid arthritis. In addition, the interaction of HA with the leukocyte receptor CD44 is important in tissue-specific homing by leukocytes, and overexpression of HA receptors has been correlated with tumor metastasis. HAS2 is a member of the newly identified vertebrate gene family encoding putative hyaluronan synthases, and its amino acid sequence shows significant homology to glycosaminoglycan synthetase (DG42) from Xenopus laevis, and human and murine hyaluronan synthase 1. [provided by RefSeq, Jul 2008]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human HAS2
Antigen Species
Human
Gene Name
HAS2
Gene ID
3037
Protein Name
Hyaluronan synthase 2
Uniprot ID
Q92819
Function
Plays a role in hyaluronan/hyaluronic acid (HA) synthesis.
Chemical Properties
Molecular WeightTheoretical: 64 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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