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SARS-CoV-2 NSP8 Protein (His)
(Synonyms: SARS-CoV 2 nsp8) Copy Product InfoSynonyms: SARS-CoV 2 nsp8
Catalog No. TMPJ-01428 Copy Product Info
Cleavage by the viral main protease, 3CLpro results in generating the nsp8 protein, The nsp8 protein has been shown to associate with several other nsps and to colocalize with these nsps in cytoplasmic complexes that are important for viral RNA synthesis. It forms a hexadecamer with nsp7 (8 subunits of each) that may participate in viral replication by acting as a primase. Alternatively, may synthesize substantially longer products than oligonucleotide primers.Nsp8 was shown to have RNA-dependent RNA polymerase (RdRp) activity that could be involved in producing primers utilized by nsp12 which is normally accepted to be the RdRp for SARS-CoV.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $95 | 35 days | 35 days | |
| 10 μg | $153 | 35 days | 35 days | |
| 20 μg | $246 | 35 days | 35 days | |
| 50 μg | $465 | 35 days | 35 days | |
| 100 μg | $767 | 35 days | 35 days | |
| 200 μg | $1,270 | 35 days | 35 days | |
| 500 μg | $2,480 | 35 days | 35 days | |
| 1 mg | $3,720 | 35 days | 35 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Cleavage by the viral main protease, 3CLpro results in generating the nsp8 protein, The nsp8 protein has been shown to associate with several other nsps and to colocalize with these nsps in cytoplasmic complexes that are important for viral RNA synthesis. It forms a hexadecamer with nsp7 (8 subunits of each) that may participate in viral replication by acting as a primase. Alternatively, may synthesize substantially longer products than oligonucleotide primers.Nsp8 was shown to have RNA-dependent RNA polymerase (RdRp) activity that could be involved in producing primers utilized by nsp12 which is normally accepted to be the RdRp for SARS-CoV. |
| Species | SARS-CoV-2 |
| Expression System | E. coli |
| Tag | C-6xHis |
| Accession Number | YP_009725304.1 |
| Amino Acid | Ala1-Gln198 |
| Construction | Ala1-Gln198 |
| Protein Purity | Greater than 85% as determined by reducing SDS-PAGE. (QC verified) |
| Formulation | Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, 10% Glycerol, pH 8.5. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | Proteins are shipped with blue ice. |
| Synonyms | SARS-CoV 2 nsp8 |
| Research Background |
| Molecular Weight | 25 KDa (reducing condition) |
| Storage | Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: SARS-CoV-2 NSP8 Protein (His) chemical structure | SARS-CoV-2 NSP8 Protein (His) molecular weight
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