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Anti-ZAP70 Monoclonal Antibody (3S447)
(Synonyms: ZAP-70, TZK, STD, STCD, SRK, IMD48, ADMIO2) Copy Product Info
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Synonyms: ZAP-70, TZK, STD, STCD, SRK, IMD48, ADMIO2
Catalog No. TMAT-1047 Copy Product Info
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Anti-ZAP70 Monoclonal Antibody (3S447) is a Mouse antibody targeting ZAP70. Anti-ZAP70 Monoclonal Antibody (3S447) can be used in WB,FCM.
Anti-ZAP70 Monoclonal Antibody
(3S447)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-ZAP70 Monoclonal Antibody (3S447) is a Mouse antibody targeting ZAP70. Anti-ZAP70 Monoclonal Antibody (3S447) can be used in WB,FCM. |
| Synonyms | ZAP-70, TZK, STD, STCD, SRK, IMD48, ADMIO2 |
| Ig Type | IgG1 |
| Clone | 3S447 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human ZAP70 (AA: 169-390) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | ZAP70 |
| Gene ID | |
| Protein Name | Tyrosine-protein kinase ZAP-70 |
| Uniprot ID |
| Molecular Weight | Theoretical: 69.9 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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