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Anti-ZAP70 Monoclonal Antibody (1G987)
(Synonyms: TZK, STD, SRK) Copy Product Info
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Synonyms: TZK, STD, SRK
Catalog No. TMAT-1046 Copy Product Info
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Anti-ZAP70 Monoclonal Antibody (1G987) is a Mouse antibody targeting ZAP70. Anti-ZAP70 Monoclonal Antibody (1G987) can be used in WB,IHC.
Anti-ZAP70 Monoclonal Antibody
(1G987)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Chemical Properties
Stability & Storage
| Description | Anti-ZAP70 Monoclonal Antibody (1G987) is a Mouse antibody targeting ZAP70. Anti-ZAP70 Monoclonal Antibody (1G987) can be used in WB,IHC. |
| Synonyms | TZK, STD, SRK |
| Ig Type | IgG1 |
| Clone | 1G987 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | ZAP70 (zeta-chain associated protein kinase), a 70 kDa member of the SYK tyrosine kinase family, plays a central role in lymphocyte activation and development, and is implicated in several immune disorders. ZAP70 controls TCR(T-cell antigen receptor)-linked signal transduction pathways. Its key role in thymocytes development and mature T lymphocytes activation has been illustrated by the characterization of several human immunodeficiencies presenting with mutations in the ZAP70 gene. ZAP70 is also expressed in several types of B-cell neoplasm and is easily detected by immunohistochemistry, providing a useful prognostic marker in patients with chronic lymphocytic leukaemia. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human ZAP70 expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | ZAP70 |
| Gene ID | |
| Protein Name | Tyrosine-protein kinase ZAP-70 |
| Uniprot ID |
| Molecular Weight | Theoretical: 70 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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