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Anti-XPC Monoclonal Antibody (1Y637)
(Synonyms: XPCC, XP3, RAD4, p125) Copy Product Info
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Synonyms: XPCC, XP3, RAD4, p125
Catalog No. TMAT-1194 Copy Product Info
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Anti-XPC Monoclonal Antibody (1Y637) is a Mouse antibody targeting XPC. Anti-XPC Monoclonal Antibody (1Y637) can be used in WB,IHC,IF,FCM.
Anti-XPC Monoclonal Antibody
(1Y637)
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Product Introduction
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Related Conjugates and Formulations
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Chemical Properties
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| Description | Anti-XPC Monoclonal Antibody (1Y637) is a Mouse antibody targeting XPC. Anti-XPC Monoclonal Antibody (1Y637) can be used in WB,IHC,IF,FCM. |
| Synonyms | XPCC, XP3, RAD4, p125 |
| Ig Type | IgG1 |
| Clone | 1Y637 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000; IF: 1/50-1/200; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene is a key component of the XPC complex, which plays an important role in the early steps of global genome nucleotide excision repair (NER). The encoded protein is important for damage sensing and DNA binding, and shows a preference for single-stranded DNA. Mutations in this gene or some other NER components can result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human XPC (AA: 32-133) expressed in mammalian. |
| Antigen Species | Human |
| Gene Name | XPC |
| Gene ID | |
| Protein Name | DNA repair protein complementing XP-C cells |
| Uniprot ID |
| Molecular Weight | Theoretical: 106 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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