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Anti-XIAP Monoclonal Antibody (2D738)
(Synonyms: XLP2, MIHA, ILP1, IAP-3, hIAP-3, hIAP3, BIRC4, API3) Copy Product Info
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Synonyms: XLP2, MIHA, ILP1, IAP-3, hIAP-3, hIAP3, BIRC4, API3
Catalog No. TMAT-1179 Copy Product Info
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Anti-XIAP Monoclonal Antibody (2D738) is a Mouse antibody targeting XIAP. Anti-XIAP Monoclonal Antibody (2D738) can be used in FCM.
Anti-XIAP Monoclonal Antibody
(2D738)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-XIAP Monoclonal Antibody (2D738) is a Mouse antibody targeting XIAP. Anti-XIAP Monoclonal Antibody (2D738) can be used in FCM. |
| Synonyms | XLP2, MIHA, ILP1, IAP-3, hIAP-3, hIAP3, BIRC4, API3 |
| Ig Type | IgG2b |
| Clone | 2D738 |
| Reactivity | Human |
| Application | |
| Recommended Dose | FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.[provided by RefSeq, Feb 2011] |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human XIAP (AA: 1-268) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | XIAP |
| Gene ID | |
| Protein Name | E3 ubiquitin-protein ligase XIAP |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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