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Synonyms: INT1
Anti-WNT1 Monoclonal Antibody
(2L282)

| Description | Anti-WNT1 Monoclonal Antibody (2L282) is a Mouse antibody targeting WNT1. Anti-WNT1 Monoclonal Antibody (2L282) can be used in WB,IHC,IF,FCM. |
| Synonyms | INT1 |
| Ig Type | IgG1 |
| Clone | 2L282 |
| Reactivity | Human,Mouse |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000; IF: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | WNT1: wingless-type MMTV integration site family, member 1. The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is very conserved in evolution, and the protein encoded by this gene is known to be 98% identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant rolein Joubert syndrome. This gene is clustered with another family member, WNT10B, in the chromosome 12q13 region. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of WNT1 expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | WNT1 |
| Gene ID | |
| Protein Name | Proto-oncogene Wnt-1 |
| Uniprot ID |
| Molecular Weight | Theoretical: 41 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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