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Anti-WNT1 Monoclonal Antibody (2L282)

(Synonyms: INT1) Copy Product Info
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Synonyms: INT1

Catalog No. TMAT-0690 Copy Product Info
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Anti-WNT1 Monoclonal Antibody (2L282) is a Mouse antibody targeting WNT1. Anti-WNT1 Monoclonal Antibody (2L282) can be used in WB,IHC,IF,FCM.

Anti-WNT1 Monoclonal Antibody
(2L282)

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Product Introduction

Bioactivity
Description
Anti-WNT1 Monoclonal Antibody (2L282) is a Mouse antibody targeting WNT1. Anti-WNT1 Monoclonal Antibody (2L282) can be used in WB,IHC,IF,FCM.
SynonymsINT1
Ig Type
IgG1
Clone
2L282
Reactivity
Human,Mouse
Application
Recommended Dose
WB: 1/500-1/2000; IHC: 1/200-1/1000; IF: 1/200-1/1000; FCM: 1/200-1/400
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationPBS with 0.05% sodium azide.
Concentration1 mg/mL
Research BackgroundWNT1: wingless-type MMTV integration site family, member 1. The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is very conserved in evolution, and the protein encoded by this gene is known to be 98% identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant rolein Joubert syndrome. This gene is clustered with another family member, WNT10B, in the chromosome 12q13 region.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Purified recombinant fragment of WNT1 expressed in E. Coli.
Antigen Species
Human
Gene Name
WNT1
Gene ID
Protein Name
Proto-oncogene Wnt-1
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 41 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: Anti-WNT1 Monoclonal Antibody (2L282) molecular weight