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Anti-WHSC2 Monoclonal Antibody (1U118)
(Synonyms: P/OKcl.15, NELF-A, NELFA) Copy Product Info
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Synonyms: P/OKcl.15, NELF-A, NELFA
Catalog No. TMAT-1544 Copy Product Info
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Anti-WHSC2 Monoclonal Antibody (1U118) is a Mouse antibody targeting WHSC2. Anti-WHSC2 Monoclonal Antibody (1U118) can be used in WB,IHC,IF,FCM.
Anti-WHSC2 Monoclonal Antibody
(1U118)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Chemical Properties
Stability & Storage
| Description | Anti-WHSC2 Monoclonal Antibody (1U118) is a Mouse antibody targeting WHSC2. Anti-WHSC2 Monoclonal Antibody (1U118) can be used in WB,IHC,IF,FCM. |
| Synonyms | P/OKcl.15, NELF-A, NELFA |
| Ig Type | IgG2b |
| Clone | 1U118 |
| Reactivity | Human,Rat |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000; IF: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93% sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human WHSC2 (AA: 280-511) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | NELFA |
| Gene ID | |
| Protein Name | Negative elongation factor A |
| Uniprot ID |
| Molecular Weight | Theoretical: 57.3 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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