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Anti-WDR5 Monoclonal Antibody (6U458)
(Synonyms: WDR5, SWD3, BIG-3) Copy Product Info
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Synonyms: WDR5, SWD3, BIG-3
Catalog No. TMAT-1156 Copy Product Info
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Anti-WDR5 Monoclonal Antibody (6U458) is a Mouse antibody targeting WDR5. Anti-WDR5 Monoclonal Antibody (6U458) can be used in WB.
Anti-WDR5 Monoclonal Antibody
(6U458)
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Product Introduction
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Related Conjugates and Formulations
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Chemical Properties
Stability & Storage
| Description | Anti-WDR5 Monoclonal Antibody (6U458) is a Mouse antibody targeting WDR5. Anti-WDR5 Monoclonal Antibody (6U458) can be used in WB. |
| Synonyms | WDR5, SWD3, BIG-3 |
| Ig Type | IgG2b |
| Clone | 6U458 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | WD-repeat protein 5 (WDR5, also designated BMP-2-induced gene 3 kb or BIG-3) belongs to the family of WD-40 repeat proteins, and is essential for vertebrate development, Hox gene activation and global H3K4 trimethylation. WDR5 is a conserved subunit of Trithorax (TRX) histone methyltransferase complexes that selectively binds to dimethylated Lys4 (K4me2) in Histone H3 to promote K4 trimethylation by TRX. It is expressed in osteoblasts, chondrocytes, osteocytes and marrow stromal cells. The WDR5 protein contains 7 WD-repeats, which may play a role in its function of accelerating osteoblast differentiation. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human WDR5 expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | WDR5 |
| Gene ID | |
| Protein Name | WD repeat-containing protein 5 |
| Uniprot ID |
| Molecular Weight | Theoretical: 36.6 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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