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Anti-VWC2 Antibody (4J499) (Synonyms: von Willebrand factor C domain containing 2, UNQ739, PSST739)

Catalog No. TMAY-02219 Copy Product Info
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Anti-VWC2 Antibody (4J499) is a Rabbit antibody targeting VWC2. Anti-VWC2 Antibody (4J499) can be used in ELISA.

Anti-VWC2 Antibody (4J499)

Copy Product Info
🥰Excellent
Catalog No. TMAY-02219
Synonyms von Willebrand factor C domain containing 2, UNQ739, PSST739

Anti-VWC2 Antibody (4J499) is a Rabbit antibody targeting VWC2. Anti-VWC2 Antibody (4J499) can be used in ELISA.

Anti-VWC2 Antibody
(4J499)
Pack SizePriceUSA StockGlobal StockQuantity
100 μL$2687-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-VWC2 Antibody (4J499) is a Rabbit antibody targeting VWC2. Anti-VWC2 Antibody (4J499) can be used in ELISA.
Synonymsvon Willebrand factor C domain containing 2, UNQ739, PSST739
Ig Type
Rabbit IgG
Clone
4J499
Reactivity
Human
Specificity
Human VWC2
Application
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human VWC2 (rh VWC2; TMPY-01755; NP_940972.2; Met 1-Met 325).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundBrorin, also known as brain-specific chordin-like protein, von Willebrand factor C domain-containing protein 2 and VWC2, is a secreted protein that contains two VWFC domains. VWC2 / Brorin is a BMP antagonist that may play a role in neural development. It promotes cell adhesion. VWC2 / Brorin is a unique member of the chordin family. It inhibited the activity of bone morphogenetic protein 2 (BMP2) and BMP6 in mouse preosteoblastic MC3T3-E1 cells. Mouse Brorin was predominantly expressed in neural tissues in embryos and also predominantly expressed in the adult brain. In the brain, the expression was detected in neurons, but not glial cells. The neural tissue-specific expression profile of Brorin is quite distinct from that of any other member of the Chordin family. VWC2 / Brorin protein promoted neurogenesis, but not astrogenesis, in mouse neural precursor cells. VWC2 / Brorin is a novel secreted BMP antagonist that potentially plays roles in neural development and functions.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human VWC2 protein (TMPY-01755)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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