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Anti-VWC2 Antibody (4J499)
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Catalog No. TMAY-02219
Alias von Willebrand factor C domain containing 2, UNQ739, PSST739
Anti-VWC2 Antibody (4J499) is a Rabbit antibody targeting VWC2. Anti-VWC2 Antibody (4J499) can be used in ELISA.
Anti-VWC2 Antibody (4J499)
Anti-VWC2 Antibody (4J499)
😃Good
Catalog No. TMAY-02219Alias von Willebrand factor C domain containing 2, UNQ739, PSST739
Anti-VWC2 Antibody (4J499) is a Rabbit antibody targeting VWC2. Anti-VWC2 Antibody (4J499) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $268 | 7-10 days |
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Product Introduction
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Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-VWC2 Antibody (4J499) is a Rabbit antibody targeting VWC2. Anti-VWC2 Antibody (4J499) can be used in ELISA. |
| Alias | von Willebrand factor C domain containing 2, UNQ739, PSST739 |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 4J499 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human VWC2 (rh VWC2; TMPY-01755; NP_940972.2; Met 1-Met 325). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Brorin, also known as brain-specific chordin-like protein, von Willebrand factor C domain-containing protein 2 and VWC2, is a secreted protein that contains two VWFC domains. VWC2 / Brorin is a BMP antagonist that may play a role in neural development. It promotes cell adhesion. VWC2 / Brorin is a unique member of the chordin family. It inhibited the activity of bone morphogenetic protein 2 (BMP2) and BMP6 in mouse preosteoblastic MC3T3-E1 cells. Mouse Brorin was predominantly expressed in neural tissues in embryos and also predominantly expressed in the adult brain. In the brain, the expression was detected in neurons, but not glial cells. The neural tissue-specific expression profile of Brorin is quite distinct from that of any other member of the Chordin family. VWC2 / Brorin protein promoted neurogenesis, but not astrogenesis, in mouse neural precursor cells. VWC2 / Brorin is a novel secreted BMP antagonist that potentially plays roles in neural development and functions. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human VWC2 protein (TMPY-01755) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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