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Anti-VWC2 Antibody (3I234)

😃Good
Catalog No. TMAY-02218
Alias von Willebrand factor C domain containing 2, UNQ739, PSST739

Anti-VWC2 Antibody (3I234) is a Mouse antibody targeting VWC2. Anti-VWC2 Antibody (3I234) can be used in ELISA(Cap).

Anti-VWC2 Antibody (3I234)

Anti-VWC2 Antibody (3I234)

😃Good
Catalog No. TMAY-02218Alias von Willebrand factor C domain containing 2, UNQ739, PSST739
Anti-VWC2 Antibody (3I234) is a Mouse antibody targeting VWC2. Anti-VWC2 Antibody (3I234) can be used in ELISA(Cap).
Pack SizePriceAvailabilityQuantity
20 μL$70 7-10 days
100 μL$199 7-10 days
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Product Introduction

Bioactivity
Description
Anti-VWC2 Antibody (3I234) is a Mouse antibody targeting VWC2. Anti-VWC2 Antibody (3I234) can be used in ELISA(Cap).
Aliasvon Willebrand factor C domain containing 2, UNQ739, PSST739
Ig Type
Monoclonal Mouse IgG1
Clone
3I234
Reactivity
Human
Application
ELISA(Cap)
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human VWC2 (rh VWC2; TMPY-01755; NP_940972.2; Met1-Met325). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundBrorin, also known as brain-specific chordin-like protein, von Willebrand factor C domain-containing protein 2 and VWC2, is a secreted protein that contains two VWFC domains. VWC2 / Brorin is a BMP antagonist that may play a role in neural development. It promotes cell adhesion. VWC2 / Brorin is a unique member of the chordin family. It inhibited the activity of bone morphogenetic protein 2 (BMP2) and BMP6 in mouse preosteoblastic MC3T3-E1 cells. Mouse Brorin was predominantly expressed in neural tissues in embryos and also predominantly expressed in the adult brain. In the brain, the expression was detected in neurons, but not glial cells. The neural tissue-specific expression profile of Brorin is quite distinct from that of any other member of the Chordin family. VWC2 / Brorin protein promoted neurogenesis, but not astrogenesis, in mouse neural precursor cells. VWC2 / Brorin is a novel secreted BMP antagonist that potentially plays roles in neural development and functions.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human VWC2 Protein (TMPY-01755)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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