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Anti-UBB Monoclonal Antibody (2N818)
(Synonyms: UBC, UBA52, RPS27A) Copy Product Info
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Synonyms: UBC, UBA52, RPS27A
Catalog No. TMAT-0787 Copy Product Info
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Anti-UBB Monoclonal Antibody (2N818) is a Mouse antibody targeting UBB. Anti-UBB Monoclonal Antibody (2N818) can be used in WB,FCM.
Anti-UBB Monoclonal Antibody
(2N818)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-UBB Monoclonal Antibody (2N818) is a Mouse antibody targeting UBB. Anti-UBB Monoclonal Antibody (2N818) can be used in WB,FCM. |
| Synonyms | UBC, UBA52, RPS27A |
| Ig Type | IgG1 |
| Clone | 2N818 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin is required for ATP-dependent, nonlysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation. Ubiquitin also binds to histone H2A in actively transcribed regions but does not cause histone H2A degradation, suggesting that ubiquitin is also involved in regulation of gene expression. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. Aberrant form of this protein has been noticed in patients with Alzheimer's and Down syndrome. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human UBB expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | UBB |
| Gene ID | |
| Protein Name | Polyubiquitin-B |
| Uniprot ID |
| Molecular Weight | Theoretical: 26 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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