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Anti-TTF1/NKX2-1 Antibody (6Z362)
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Catalog No. TMAB-13883
Anti-TTF1/NKX2-1 Antibody (6Z362) is a Mouse antibody targeting TTF1/NKX2-1. Anti-TTF1/NKX2-1 Antibody (6Z362) can be used in IHC-P,IHC-Fr,IF.
Anti-TTF1/NKX2-1 Antibody (6Z362)
Anti-TTF1/NKX2-1 Antibody (6Z362)
😃Good
Catalog No. TMAB-13883
Anti-TTF1/NKX2-1 Antibody (6Z362) is a Mouse antibody targeting TTF1/NKX2-1. Anti-TTF1/NKX2-1 Antibody (6Z362) can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-TTF1/NKX2-1 Antibody (6Z362) is a Mouse antibody targeting TTF1/NKX2-1. Anti-TTF1/NKX2-1 Antibody (6Z362) can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG1, Kappa |
| Clone | 6Z362 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Nucleus. |
| Tissue Specificity | Thyroid, lung and CNS. Expressed in restricted regions of the developing brain within the diencephalon, in parts of the hypothalamus and neurohypophysis, and in the telencephalon. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | PBS, pH7.2, 0.02% Porcolin 300, containing stabilizing protein. |
| Concentration | 1mg/ml |
| Research Background | This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TFF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription. [provided by RefSeq, Apr 2011] |
| Immunogen | KLH conjugated synthetic peptide: human TTF-1 |
| Antigen Species | Human |
| Gene Name | NKX2-1 |
| Gene ID | |
| Protein Name | Homeobox protein Nkx-2.1 |
| Uniprot ID | |
| Function | Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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