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Synonyms: fsTnI, FSSV, DA2B, AMCD2B
Anti-TNNI2 Monoclonal Antibody
(2C659)

| Description | Anti-TNNI2 Monoclonal Antibody (2C659) is a Mouse antibody targeting TNNI2. Anti-TNNI2 Monoclonal Antibody (2C659) can be used in IF,FCM. |
| Synonyms | fsTnI, FSSV, DA2B, AMCD2B |
| Ig Type | IgG1 |
| Clone | 2C659 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IF: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been found for this gene. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human TNNI2 expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | TNNI2 |
| Gene ID | |
| Protein Name | Troponin I, fast skeletal muscle |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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