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Anti-TNFRSF1A Monoclonal Antibody (6Z130)

(Synonyms: TNF-R-I, TNFR60, TNF-R55, TNFR55, TNFR1, TNF-R, TNFAR, TBP1, p60, p55-R, p55, FPF, CD120a) Copy Product Info
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Synonyms: TNF-R-I, TNFR60, TNF-R55, TNFR55, TNFR1, TNF-R, TNFAR, TBP1, p60, p55-R, p55, FPF, CD120a

Catalog No. TMAT-0890 Copy Product Info
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Anti-TNFRSF1A Monoclonal Antibody (6Z130) is a Mouse antibody targeting TNFRSF1A. Anti-TNFRSF1A Monoclonal Antibody (6Z130) can be used in IF,FCM.

Anti-TNFRSF1A Monoclonal Antibody
(6Z130)

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Product Introduction

Bioactivity
Description
Anti-TNFRSF1A Monoclonal Antibody (6Z130) is a Mouse antibody targeting TNFRSF1A. Anti-TNFRSF1A Monoclonal Antibody (6Z130) can be used in IF,FCM.
SynonymsTNF-R-I, TNFR60, TNF-R55, TNFR55, TNFR1, TNF-R, TNFAR, TBP1, p60, p55-R, p55, FPF, CD120a
Ig Type
IgG1
Clone
6Z130
Reactivity
Human
Application
Recommended Dose
IF: 1/200-1/1000; FCM: 1/200-1/400
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationPBS with 0.05% sodium azide
Concentration1 mg/mL
Research BackgroundThis gene encodes a member of the TNF receptor superfamily of proteins. The encoded receptor is found in membrane-bound and soluble forms that interact with membrane-bound and soluble forms, respectively, of its ligand, tumor necrosis factor alpha. Binding of membrane-bound tumor necrosis factor alpha to the membrane-bound receptor induces receptor trimerization and activation, which plays a role in cell survival, apoptosis, and inflammation. Proteolytic processing of the encoded receptor results in release of the soluble form of the receptor, which can interact with free tumor necrosis factor alpha to inhibit inflammation. Mutations in this gene underlie tumor necrosis factor receptor-associated periodic syndrome (TRAPS), characterized by fever, abdominal pain and other features. Mutations in this gene may also be associated with multiple sclerosis in human patients.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Purified recombinant fragment of human TNFRSF1A (AA: extra 30-211) expressed in E. Coli.
Antigen Species
Human
Gene Name
TNFRSF1A
Gene ID
Protein Name
Tumor necrosis factor receptor superfamily member 1A
Uniprot ID
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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