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Synonyms: GITR-D, GITR, CD357, AITR
Anti-TNFRSF18 Monoclonal Antibody
(1D568)

| Description | Anti-TNFRSF18 Monoclonal Antibody (1D568) is a Mouse antibody targeting TNFRSF18. Anti-TNFRSF18 Monoclonal Antibody (1D568) can be used in IHC,FCM. |
| Synonyms | GITR-D, GITR, CD357, AITR |
| Ig Type | IgG1 |
| Clone | 1D568 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human TNFRSF18 (AA: extra 26-162) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | TNFRSF18 |
| Gene ID | |
| Protein Name | Tumor necrosis factor receptor superfamily member 18 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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