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Anti-TMEM119 Antibody (7P728)
Catalog No. TMAB-13591 Copy Product Info
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Anti-TMEM119 Antibody (7P728) is a Mouse antibody targeting TMEM119. Anti-TMEM119 Antibody (7P728) can be used in WB.
Anti-TMEM119 Antibody (7P728)
Copy Product Info🥰Excellent
Catalog No. TMAB-13591
Anti-TMEM119 Antibody (7P728) is a Mouse antibody targeting TMEM119. Anti-TMEM119 Antibody (7P728) can be used in WB.
Anti-TMEM119 Antibody
(7P728)
(7P728)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 25 μL | $166 | 7-10 days | 7-10 days | |
| 50 μL | $297 | 7-10 days | 7-10 days | |
| 100 μL | $470 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-TMEM119 Antibody (7P728) is a Mouse antibody targeting TMEM119. Anti-TMEM119 Antibody (7P728) can be used in WB. |
| Ig Type | IgG3/Kappa |
| Clone | 7P728 |
| Reactivity | Mouse (predicted:Rat,Human) |
| Verified Activity | 25 μg total protein per lane of various lysates (see on figure) probed with TMEM119 monoclonal antibody, unconjugated (TMAB-13591) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min. |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Cell membrane;Single-pass type I membrane protein;Cytoplasm;Endoplasmic reticulum membrane |
| Tissue Specificity | Expressed in brain microglia (at protein level). Elevated expression levels seen in the brain of patients with Alzheimer disease. Expressed by osteoblast-like cells in bone tissues and follicular dendritic cells in lymphoid tissues. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Involved in positive regulation of bone mineralization; positive regulation of osteoblast differentiation; and positive regulation of osteoblast proliferation. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] |
| Immunogen | KLH conjugated synthetic peptide: human TMEM119 |
| Antigen Species | Human |
| Gene Name | TMEM119 |
| Gene ID | |
| Protein Name | Transmembrane protein 119 |
| Function | Plays an important role in bone formation and normal bone mineralization. Promotes the differentiation of myoblasts into osteoblasts (PubMed:20025746).May induce the commitment and differentiation of myoblasts into osteoblasts through an enhancement of BMP2 production and interaction with the BMP-RUNX2 pathway. Up-regulates the expression of ATF4, a transcription factor which plays a central role in osteoblast differentiation. Essential for normal spermatogenesis and late testicular differentiation (By similarity). |
| Molecular Weight | Theoretical: 29 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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