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Anti-TMEM119 Antibody (7P728)

😃Good
Catalog No. TMAB-13591

Anti-TMEM119 Antibody (7P728) is a Mouse antibody targeting TMEM119. Anti-TMEM119 Antibody (7P728) can be used in WB.

Anti-TMEM119 Antibody (7P728)

Anti-TMEM119 Antibody (7P728)

😃Good
Catalog No. TMAB-13591
Anti-TMEM119 Antibody (7P728) is a Mouse antibody targeting TMEM119. Anti-TMEM119 Antibody (7P728) can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1667-10 days7-10 days
50 μL$2977-10 days7-10 days
100 μL$4707-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-TMEM119 Antibody (7P728) is a Mouse antibody targeting TMEM119. Anti-TMEM119 Antibody (7P728) can be used in WB.
Ig Type
IgG3/Kappa
Clone
7P728
Reactivity
Mouse (predicted:Rat,Human)
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Monoclonal
Host SpeciesMouse
Subcellular LocalizationCell membrane;Single-pass type I membrane protein;Cytoplasm;Endoplasmic reticulum membrane
Tissue SpecificityExpressed in brain microglia (at protein level). Elevated expression levels seen in the brain of patients with Alzheimer disease. Expressed by osteoblast-like cells in bone tissues and follicular dendritic cells in lymphoid tissues.
ConstructionHybridoma Monoclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundInvolved in positive regulation of bone mineralization; positive regulation of osteoblast differentiation; and positive regulation of osteoblast proliferation. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human TMEM119
Antigen Species
Human
Gene Name
TMEM119
Gene ID
Protein Name
Transmembrane protein 119
Function
Plays an important role in bone formation and normal bone mineralization. Promotes the differentiation of myoblasts into osteoblasts (PubMed:20025746).May induce the commitment and differentiation of myoblasts into osteoblasts through an enhancement of BMP2 production and interaction with the BMP-RUNX2 pathway. Up-regulates the expression of ATF4, a transcription factor which plays a central role in osteoblast differentiation. Essential for normal spermatogenesis and late testicular differentiation (By similarity).
Chemical Properties
Molecular WeightTheoretical: 29 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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