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Anti-TIM3 Monoclonal Antibody (1U175)
(Synonyms: TIMD-3, TIMD3, Tim-3, KIM-3, HAVcr-2, HAVCR2, CD366) Copy Product Info
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Synonyms: TIMD-3, TIMD3, Tim-3, KIM-3, HAVcr-2, HAVCR2, CD366
Catalog No. TMAT-1440 Copy Product Info
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Anti-TIM3 Monoclonal Antibody (1U175) is a Mouse antibody targeting TIM3. Anti-TIM3 Monoclonal Antibody (1U175) can be used in IF,FCM.
Anti-TIM3 Monoclonal Antibody
(1U175)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Stability & Storage
| Description | Anti-TIM3 Monoclonal Antibody (1U175) is a Mouse antibody targeting TIM3. Anti-TIM3 Monoclonal Antibody (1U175) can be used in IF,FCM. |
| Synonyms | TIMD-3, TIMD3, Tim-3, KIM-3, HAVcr-2, HAVCR2, CD366 |
| Ig Type | IgG1 |
| Clone | 1U175 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IF: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human TIM3 (AA: extra 22-202) expressed in HEK293 cells. |
| Antigen Species | Human |
| Gene Name | HAVCR2 |
| Gene ID | |
| Protein Name | Hepatitis A virus cellular receptor 2 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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