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Anti-TDP43 Monoclonal Antibody (8C410)
(Synonyms: TDP-43, ALS10) Copy Product Info
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Synonyms: TDP-43, ALS10
Catalog No. TMAT-1263 Copy Product Info
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Anti-TDP43 Monoclonal Antibody (8C410) is a Mouse antibody targeting TDP43. Anti-TDP43 Monoclonal Antibody (8C410) can be used in WB,IHC,IF,FCM.
Anti-TDP43 Monoclonal Antibody
(8C410)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Chemical Properties
Stability & Storage
| Description | Anti-TDP43 Monoclonal Antibody (8C410) is a Mouse antibody targeting TDP43. Anti-TDP43 Monoclonal Antibody (8C410) can be used in WB,IHC,IF,FCM. |
| Synonyms | TDP-43, ALS10 |
| Ig Type | IgG1 |
| Clone | 8C410 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000; IF: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq, Jul 2008] |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human TDP43 (AA: free peptide) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | TARDBP |
| Gene ID | |
| Protein Name | TAR DNA-binding protein 43 |
| Uniprot ID |
| Molecular Weight | Theoretical: 44.7 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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