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Anti-TCF7 Monoclonal Antibody (3B295)

(Synonyms: TCF-1) Copy Product Info
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Synonyms: TCF-1

Catalog No. TMAT-0999 Copy Product Info
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Anti-TCF7 Monoclonal Antibody (3B295) is a Mouse antibody targeting TCF7. Anti-TCF7 Monoclonal Antibody (3B295) can be used in IHC,IF,FCM.

Anti-TCF7 Monoclonal Antibody
(3B295)

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Product Introduction

Bioactivity
Description
Anti-TCF7 Monoclonal Antibody (3B295) is a Mouse antibody targeting TCF7. Anti-TCF7 Monoclonal Antibody (3B295) can be used in IHC,IF,FCM.
SynonymsTCF-1
Ig Type
IgG1
Clone
3B295
Reactivity
Human
Application
Recommended Dose
IHC: 1/200-1/1000; IF: 1/50-1/200; FCM: 1/200-1/400
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationPBS with 0.05% sodium azide
Concentration1 mg/mL
Research BackgroundThis gene encodes a member of the T-cell factor/lymphoid enhancer-binding factor family of high mobility group (HMG) box transcriptional activators. This gene is expressed predominantly in T-cells and plays a critical role in natural killer cell and innate lymphoid cell development. The encoded protein forms a complex with beta-catenin and activates transcription through a Wnt/beta-catenin signaling pathway. Mice with a knockout of this gene are viable and fertile, but display a block in T-lymphocyte differentiation. Alternative splicing results in multiple transcript variants. Naturally-occurring isoforms lacking the N-terminal beta-catenin interaction domain may act as dominant negative regulators of Wnt signaling.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Purified recombinant fragment of human TCF7 (AA: 168-358) expressed in E. Coli.
Antigen Species
Human
Gene Name
TCF7
Gene ID
Protein Name
Transcription factor 7
Uniprot ID
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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