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Synonyms: TCF-1
Anti-TCF7 Monoclonal Antibody
(3B295)

| Description | Anti-TCF7 Monoclonal Antibody (3B295) is a Mouse antibody targeting TCF7. Anti-TCF7 Monoclonal Antibody (3B295) can be used in IHC,IF,FCM. |
| Synonyms | TCF-1 |
| Ig Type | IgG1 |
| Clone | 3B295 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000; IF: 1/50-1/200; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a member of the T-cell factor/lymphoid enhancer-binding factor family of high mobility group (HMG) box transcriptional activators. This gene is expressed predominantly in T-cells and plays a critical role in natural killer cell and innate lymphoid cell development. The encoded protein forms a complex with beta-catenin and activates transcription through a Wnt/beta-catenin signaling pathway. Mice with a knockout of this gene are viable and fertile, but display a block in T-lymphocyte differentiation. Alternative splicing results in multiple transcript variants. Naturally-occurring isoforms lacking the N-terminal beta-catenin interaction domain may act as dominant negative regulators of Wnt signaling. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human TCF7 (AA: 168-358) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | TCF7 |
| Gene ID | |
| Protein Name | Transcription factor 7 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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