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Anti-TARDBP Monoclonal Antibody (1G220)

(Synonyms: TDP-43, ALS10) Copy Product Info
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Synonyms: TDP-43, ALS10

Catalog No. TMAT-1262 Copy Product Info
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Anti-TARDBP Monoclonal Antibody (1G220) is a Mouse antibody targeting TARDBP. Anti-TARDBP Monoclonal Antibody (1G220) can be used in FCM.

Anti-TARDBP Monoclonal Antibody
(1G220)

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Product Introduction

Bioactivity
Description
Anti-TARDBP Monoclonal Antibody (1G220) is a Mouse antibody targeting TARDBP. Anti-TARDBP Monoclonal Antibody (1G220) can be used in FCM.
SynonymsTDP-43, ALS10
Ig Type
IgG1
Clone
1G220
Reactivity
Human
Application
Recommended Dose
FCM: 1/200-1/400
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationPBS with 0.05% sodium azide
Concentration1 mg/mL
Research BackgroundHIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Purified recombinant fragment of human TARDBP (AA: 126-260) expressed in E. Coli.
Antigen Species
Human
Gene Name
TARDBP
Gene ID
Protein Name
TAR DNA-binding protein 43
Uniprot ID
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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