Shopping Cart
Remove All
Your shopping cart is currently empty
Synonyms: STAT5B, STAT5
Anti-STAT5B Monoclonal Antibody
(3T897)

| Description | Anti-STAT5B Monoclonal Antibody (3T897) is a Mouse antibody targeting STAT5B. Anti-STAT5B Monoclonal Antibody (3T897) can be used in WB. |
| Synonyms | STAT5B, STAT5 |
| Ig Type | IgG1 |
| Clone | 3T897 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human STAT5B expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | STAT5B |
| Gene ID | |
| Protein Name | Signal transducer and activator of transcription 5B |
| Uniprot ID |
| Molecular Weight | Theoretical: 90 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
|---|

Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.