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Anti-STAT5B Monoclonal Antibody (3T897)

(Synonyms: STAT5B, STAT5) Copy Product Info
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Synonyms: STAT5B, STAT5

Catalog No. TMAT-1099 Copy Product Info
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Anti-STAT5B Monoclonal Antibody (3T897) is a Mouse antibody targeting STAT5B. Anti-STAT5B Monoclonal Antibody (3T897) can be used in WB.

Anti-STAT5B Monoclonal Antibody
(3T897)

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Product Introduction

Bioactivity
Description
Anti-STAT5B Monoclonal Antibody (3T897) is a Mouse antibody targeting STAT5B. Anti-STAT5B Monoclonal Antibody (3T897) can be used in WB.
SynonymsSTAT5B, STAT5
Ig Type
IgG1
Clone
3T897
Reactivity
Human
Application
Recommended Dose
WB: 1/500-1/2000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationPBS with 0.05% sodium azide.
Concentration1 mg/mL
Research BackgroundThe protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Purified recombinant fragment of human STAT5B expressed in E. Coli.
Antigen Species
Human
Gene Name
STAT5B
Gene ID
Protein Name
Signal transducer and activator of transcription 5B
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 90 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: Anti-STAT5B Monoclonal Antibody (3T897) molecular weight