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Anti-SMAD4 Monoclonal Antibody (5J862)
(Synonyms: SMAD4, MADH4, JIP, DPC4) Copy Product Info
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Synonyms: SMAD4, MADH4, JIP, DPC4
Catalog No. TMAT-1278 Copy Product Info
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Anti-SMAD4 Monoclonal Antibody (5J862) is a Mouse antibody targeting SMAD4. Anti-SMAD4 Monoclonal Antibody (5J862) can be used in WB,IHC,IF,FCM.
Anti-SMAD4 Monoclonal Antibody
(5J862)
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Product Introduction
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Related Conjugates and Formulations
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Chemical Properties
Stability & Storage
| Description | Anti-SMAD4 Monoclonal Antibody (5J862) is a Mouse antibody targeting SMAD4. Anti-SMAD4 Monoclonal Antibody (5J862) can be used in WB,IHC,IF,FCM. |
| Synonyms | SMAD4, MADH4, JIP, DPC4 |
| Ig Type | IgG1 |
| Clone | 5J862 |
| Reactivity | Human,Mouse |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000; IF: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | Common mediator of signal transduction by TGF-beta (transforming growth factor) superfamily; SMAD4 is the common SMAD (co-SMAD). Promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. May act as a tumor suppressor Mutations or deletions in this gene have been shown to result in pancreatic cancer, juvenile polyposis syndrome, and hereditary hemorrhagic telangiectasia syndrome. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human SMAD4 expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | SMAD4 |
| Gene ID | |
| Protein Name | SMAD family member 4 |
| Uniprot ID |
| Molecular Weight | Theoretical: 65 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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