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Anti-SMAD1 Monoclonal Antibody (1E299)
(Synonyms: MADR1, MADH1, JV4-1, JV41, BSP-1, BSP1) Copy Product Info
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Synonyms: MADR1, MADH1, JV4-1, JV41, BSP-1, BSP1
Catalog No. TMAT-1346 Copy Product Info
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Anti-SMAD1 Monoclonal Antibody (1E299) is a Mouse antibody targeting SMAD1. Anti-SMAD1 Monoclonal Antibody (1E299) can be used in WB.
Anti-SMAD1 Monoclonal Antibody
(1E299)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Chemical Properties
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| Description | Anti-SMAD1 Monoclonal Antibody (1E299) is a Mouse antibody targeting SMAD1. Anti-SMAD1 Monoclonal Antibody (1E299) can be used in WB. |
| Synonyms | MADR1, MADH1, JV4-1, JV41, BSP-1, BSP1 |
| Ig Type | IgG1 |
| Clone | 1E299 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1/500-1/2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008] |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human SMAD1 (AA: 1-110) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | SMAD1 |
| Gene ID | |
| Protein Name | SMAD family member 1 |
| Uniprot ID |
| Molecular Weight | Theoretical: 52.3 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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