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Anti-SIRT6 Monoclonal Antibody (4B391)
(Synonyms: SIR2L6) Copy Product Info
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Synonyms: SIR2L6
Catalog No. TMAT-1430 Copy Product Info
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Anti-SIRT6 Monoclonal Antibody (4B391) is a Mouse antibody targeting SIRT6. Anti-SIRT6 Monoclonal Antibody (4B391) can be used in IF,FCM.
Anti-SIRT6 Monoclonal Antibody
(4B391)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-SIRT6 Monoclonal Antibody (4B391) is a Mouse antibody targeting SIRT6. Anti-SIRT6 Monoclonal Antibody (4B391) can be used in IF,FCM. |
| Synonyms | SIR2L6 |
| Ig Type | IgG1 |
| Clone | 4B391 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IF: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. Alternative splicing results in multiple transcript variants. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human SIRT6 (AA: 141-250) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | SIRT6 |
| Gene ID | |
| Protein Name | NAD-dependent protein deacylase sirtuin-6 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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