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Anti-SH2B2 Monoclonal Antibody (8B231)

(Synonyms: APS) Copy Product Info
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Synonyms: APS

Catalog No. TMAT-0589 Copy Product Info
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Anti-SH2B2 Monoclonal Antibody (8B231) is a Mouse antibody targeting SH2B2. Anti-SH2B2 Monoclonal Antibody (8B231) can be used in IHC,FCM.

Anti-SH2B2 Monoclonal Antibody
(8B231)

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Product Introduction

Bioactivity
Description
Anti-SH2B2 Monoclonal Antibody (8B231) is a Mouse antibody targeting SH2B2. Anti-SH2B2 Monoclonal Antibody (8B231) can be used in IHC,FCM.
SynonymsAPS
Ig Type
IgG2b
Clone
8B231
Reactivity
Human
Application
Recommended Dose
IHC: 1/200-1/1000; FCM: 1/200-1/400
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationPBS with 0.05% sodium azide
Concentration1 mg/ml
Research BackgroundThe protein encoded by this gene is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt's lymphoma cell lines, it is tyrosine-phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc/Grb2 pathway.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Purified recombinant fragment of human SH2B2 (AA: 497-676) expressed in E. Coli.
Antigen Species
Human
Gene Name
SH2B2
Gene ID
Protein Name
SH2B adapter protein 2
Uniprot ID
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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