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Anti-SETD7 Monoclonal Antibody (7S223)
(Synonyms: SET9, SET7/9, SET7, KMT7) Copy Product Info
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Synonyms: SET9, SET7/9, SET7, KMT7
Catalog No. TMAT-1442 Copy Product Info
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Anti-SETD7 Monoclonal Antibody (7S223) is a Mouse antibody targeting SETD7. Anti-SETD7 Monoclonal Antibody (7S223) can be used in WB,FCM.
Anti-SETD7 Monoclonal Antibody
(7S223)
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Product Introduction
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Related Conjugates and Formulations
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| Description | Anti-SETD7 Monoclonal Antibody (7S223) is a Mouse antibody targeting SETD7. Anti-SETD7 Monoclonal Antibody (7S223) can be used in WB,FCM. |
| Synonyms | SET9, SET7/9, SET7, KMT7 |
| Ig Type | IgG2a |
| Clone | 7S223 |
| Reactivity | Human,Rat,Monkey |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | Histone methyltransferase that specifically monomethylates Lys-4 of histone H3. H3 Lys-4 methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates Lys-189 of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates Lys-372 of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human SETD7 (AA: 107-366) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | SETD7 |
| Gene ID | |
| Protein Name | Histone-lysine N-methyltransferase SETD7 |
| Uniprot ID |
| Molecular Weight | Theoretical: 40.7 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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