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Anti-SCF Antibody (8L673)

😃Good
Catalog No. TMAY-00847
Alias SLF, Sl, SF, SCF, Mgf, Kitlg, KIT ligand, Gb, Con, Clo

Anti-SCF Antibody (8L673) is a Rabbit antibody targeting SCF. Anti-SCF Antibody (8L673) can be used in ELISA.

Anti-SCF Antibody (8L673)

Anti-SCF Antibody (8L673)

😃Good
Catalog No. TMAY-00847Alias SLF, Sl, SF, SCF, Mgf, Kitlg, KIT ligand, Gb, Con, Clo
Anti-SCF Antibody (8L673) is a Rabbit antibody targeting SCF. Anti-SCF Antibody (8L673) can be used in ELISA.
Pack SizePriceAvailabilityQuantity
20 μL$94 7-10 days
100 μL$270 7-10 days
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Product Introduction

Bioactivity
Description
Antibody Type: Rabbit Monoclonal

Application: ELISA

Reactivity: Human
AliasSLF, Sl, SF, SCF, Mgf, Kitlg, KIT ligand, Gb, Con, Clo
Ig Type
Rabbit IgG
Clone
8L673
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human SCF / C-kit ligand (rh SCF / C-kit ligand; TMPY-02170; P21583-1; Met1-Ala189).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundSimilar to Kit ligand precursor (C-kit ligand), also known as Stem cell factor (SCF), Mast cell growth factor (MGF), or Hematopoietic growth factor KL. SCF/C-kit ligand is the ligand of the tyrosine-kinase receptor encoded by the KIT locus. This ligand is a pleiotropic factor that acts in utero in germ cell and neural cell development, and hematopoiesis, all believed to reflect a role in cell migration. In adults, it functions pleiotropically, while mostly noted for its continued requirement in hematopoiesis. SCF/C-kit ligand stimulates the proliferation of mast cells. This protein can augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. It may act synergistically with other cytokines, probably interleukins SCF/C-kit ligand is the ligand for the tyrosine kinase receptor c-kit, which is expressed on both primitive and mature hematopoietic progenitor cells. In vitro, SCF/C-kit ligand synergizes with other growth factors, such as granulocyte colony-stimulating factor (G-CSF), granulocyte-macrophage colony-stimulating factor, and interleukin-3 to stimulate the proliferation and differentiation of cells of the lymphoid, myeloid, erythroid, and megakaryocytic lineages. In vivo, SCF/C-kit also synergizes with other growth factors and has been shown to enhance the mobilization of peripheral blood progenitor cells in combination with G-CSF. In phase I/II clinical studies administration of the combination of SCF and G-CSF resulted in a two- to threefold increase in cells that express the CD34 antigen compared with G-CSF alone.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human SCF / C-kit ligand protein (TMPY-02170)
Antigen Species
Human
Biology Area
Cardiac Stem Cell Markers
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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