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Anti-RUNX3 Monoclonal Antibody (8X583)

(Synonyms: PEBP2aC, CBFA3, AML2) Copy Product Info
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Synonyms: PEBP2aC, CBFA3, AML2

Catalog No. TMAT-1288 Copy Product Info
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Anti-RUNX3 Monoclonal Antibody (8X583) is a Mouse antibody targeting RUNX3. Anti-RUNX3 Monoclonal Antibody (8X583) can be used in IHC,IF,FCM.

Anti-RUNX3 Monoclonal Antibody
(8X583)

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Product Introduction

Bioactivity
Description
Anti-RUNX3 Monoclonal Antibody (8X583) is a Mouse antibody targeting RUNX3. Anti-RUNX3 Monoclonal Antibody (8X583) can be used in IHC,IF,FCM.
SynonymsPEBP2aC, CBFA3, AML2
Ig Type
IgG2b
Clone
8X583
Reactivity
Human
Application
Recommended Dose
IHC: 1/200-1/1000; IF: 1/50-1/250; FCM: 1/200-1/400
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationPBS with 0.05% sodium azide
Concentration1 mg/mL
Research BackgroundThis gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Purified recombinant fragment of human RUNX3 (AA: 294-429) expressed in E. Coli.
Antigen Species
Human
Gene Name
RUNX3
Gene ID
Protein Name
Runt-related transcription factor 3
Uniprot ID
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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