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Anti-RSK1 Monoclonal Antibody (1I534)
(Synonyms: RSK1, RSK, RPS6KA1, MAPKAPK1A, HU-1) Copy Product Info
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Synonyms: RSK1, RSK, RPS6KA1, MAPKAPK1A, HU-1
Catalog No. TMAT-1334 Copy Product Info
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Anti-RSK1 Monoclonal Antibody (1I534) is a Mouse antibody targeting RSK1. Anti-RSK1 Monoclonal Antibody (1I534) can be used in IHC.
Anti-RSK1 Monoclonal Antibody
(1I534)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-RSK1 Monoclonal Antibody (1I534) is a Mouse antibody targeting RSK1. Anti-RSK1 Monoclonal Antibody (1I534) can be used in IHC. |
| Synonyms | RSK1, RSK, RPS6KA1, MAPKAPK1A, HU-1 |
| Ig Type | IgG2b |
| Clone | 1I534 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | Rsk1 is a member of a family of 90kDa ribosomal protein S6 kinases, which includes Rsk1, Rsk2 and Rsk3. These are broadly expressed serine / threonine protein kinases activated in response to mitogenic stimuli, including extracellular signal regulated protein kinases Erk1 and Erk2. Rsk1 is activated by MAPK in vitro and in vivo via phosphorylation. Active Rsks appear to play a major role in transcriptional regulation by translocating to the nucleus and phosphorylating c-Fos and CREB. RSK proteins possess two separate kinase domains, the C terminal kinase domain and the N terminal kinase domain, separated by a linker region containing a hydrophobic motif. RSK is activated by many stimuli including growth factors, phorbol esters, cAMP, heat shock, and irradiation. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human RSK1 expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | RPS6KA1 |
| Gene ID | |
| Protein Name | Ribosomal protein S6 kinase alpha-1 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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