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Anti-REG3A Antibody (8V229) is a Mouse antibody targeting REG3A. Anti-REG3A Antibody (8V229) can be used in ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $198 | 7-10 days |
Description | Anti-REG3A Antibody (8V229) is a Mouse antibody targeting REG3A. Anti-REG3A Antibody (8V229) can be used in ELISA. |
Alias | regenerating family member 3 α, regenerating family member 3 alpha, REG3A, Reg3, Pap2 |
Ig Type | Monoclonal Mouse IgG1 |
Clone | 8V229 |
Reactivity | Rat |
Application | ELISA |
Recommended Dose | ELISA: 1:1000-1:2000 |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Rat REG3A (TMPY-03134; BAA04904.1; Met1-Gln174). The IgG fraction of the cell culture supernatant was purified by Protein A affinity. |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Regenerating islet-derived protein 3-alpha, also known as Regenerating islet-derived protein III-alpha, REG-3-alpha, REG3A, and HIP, is secreted protein that contains one C-type lectin domain. REG3A is constitutively expressed in intestine, and is a pancreatic secretory protein that may be involved in cell proliferation or differentiation. It is overexpressed during the acute phase of pancreatitis and in some patients with chronic pancreatitis. REG3A and REG1A proteins are both involved in liver and pancreatic regeneration and proliferation. REG3A is also a stress protein involved in the control of bacterial proliferation. REG3A is down-regulated in most primary human gastric cancer cells, and might be useful in the diagnosis of gastric cancer. Additionally, REG3A is a target of beta-catenin signaling in Huh7 hepatoma cells. The REG1A and REG3A are downstream targets of the Wnt pathway during liver tumorigenesis. |
Conjucates | Unconjugated |
Immunogen | Recombinant Rat REG3A protein (TMPY-03134) |
Antigen Species | Rat |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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