Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty

Anti-RAF1 Monoclonal Antibody (4K700)

(Synonyms: Raf-1, NS5, c-Raf, CRAF) Copy Product Info
😃Good

Synonyms: Raf-1, NS5, c-Raf, CRAF

Catalog No. TMAT-0676 Copy Product Info
😃Good
Anti-RAF1 Monoclonal Antibody (4K700) is a Mouse antibody targeting RAF1. Anti-RAF1 Monoclonal Antibody (4K700) can be used in WB,IHC,FCM.

Anti-RAF1 Monoclonal Antibody
(4K700)

TargetMol
Product information is being updated, if you want to purchase, please click the bulk custom button.
Add to Quotation
Questions
TargetMol
View More

Product Introduction

Bioactivity
Description
Anti-RAF1 Monoclonal Antibody (4K700) is a Mouse antibody targeting RAF1. Anti-RAF1 Monoclonal Antibody (4K700) can be used in WB,IHC,FCM.
SynonymsRaf-1, NS5, c-Raf, CRAF
Ig Type
IgG1
Clone
4K700
Reactivity
Human
Application
Recommended Dose
WB: 1/500-1/2000; IHC: 1/200-1/1000; FCM: 1/200-1/400
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationPBS with 0.05% sodium azide
Concentration1 mg/mL
Research BackgroundThis gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Purified recombinant fragment of human RAF1 expressed in E. Coli.
Antigen Species
Human
Gene Name
RAF1
Gene ID
Protein Name
RAF proto-oncogene serine/threonine-protein kinase
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 73 kDa
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

Calculator

  • Dilution Calculator
  • Reconstitution Calculator

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: Anti-RAF1 Monoclonal Antibody (4K700) molecular weight