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Anti-RAD18 Monoclonal Antibody (2P370)
(Synonyms: RNF73) Copy Product Info
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Synonyms: RNF73
Catalog No. TMAT-1583 Copy Product Info
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Anti-RAD18 Monoclonal Antibody (2P370) is a Mouse antibody targeting RAD18. Anti-RAD18 Monoclonal Antibody (2P370) can be used in FCM.
Anti-RAD18 Monoclonal Antibody
(2P370)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-RAD18 Monoclonal Antibody (2P370) is a Mouse antibody targeting RAD18. Anti-RAD18 Monoclonal Antibody (2P370) can be used in FCM. |
| Synonyms | RNF73 |
| Ig Type | IgG1 |
| Clone | 2P370 |
| Reactivity | Human |
| Application | |
| Recommended Dose | FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human RAD18 (AA: 332-430) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | RAD18 |
| Gene ID | |
| Protein Name | E3 ubiquitin-protein ligase RAD18 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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