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Synonyms: PTK7, CCK4
Anti-PTK7 Monoclonal Antibody
(8V401)

| Description | Anti-PTK7 Monoclonal Antibody (8V401) is a Mouse antibody targeting PTK7. Anti-PTK7 Monoclonal Antibody (8V401) can be used in WB,IHC. |
| Synonyms | PTK7, CCK4 |
| Ig Type | IgG1 |
| Clone | 8V401 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | Receptor protein tyrosine kinases transduce extracellular signals across the cell membrane. A subgroup of these kinases lack detectable catalytic tyrosine kinase activity but retain roles in signal transduction. The protein encoded by this gene is a member of this subgroup of tyrosine kinases and may function as a cell adhesion molecule. This gene is thought to be expressed in colon carcinomas but not in normal colon, and therefore may be a marker for or may be involved in tumor progression. Four transcript variants encoding four different isoforms have been found for this gene.Tissue specificity: Highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes. Weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle. Also expressed in erythroleukemia cells. But not expressed in colon. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human PTK7 expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | PTK7 |
| Gene ID | |
| Protein Name | Inactive tyrosine-protein kinase 7 |
| Uniprot ID |
| Molecular Weight | Theoretical: 118 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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