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Anti-PTK6 Monoclonal Antibody (5Q577)
(Synonyms: FLJ42088, BRK) Copy Product Info
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Synonyms: FLJ42088, BRK
Catalog No. TMAT-1292 Copy Product Info
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Anti-PTK6 Monoclonal Antibody (5Q577) is a Mouse antibody targeting PTK6. Anti-PTK6 Monoclonal Antibody (5Q577) can be used in WB.
Anti-PTK6 Monoclonal Antibody
(5Q577)
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Product Introduction
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Related Conjugates and Formulations
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Chemical Properties
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| Description | Anti-PTK6 Monoclonal Antibody (5Q577) is a Mouse antibody targeting PTK6. Anti-PTK6 Monoclonal Antibody (5Q577) can be used in WB. |
| Synonyms | FLJ42088, BRK |
| Ig Type | IgG2b |
| Clone | 5Q577 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | PTK6 (protein tyrosine kinase 6, BRK or FLJ42088), with 451-amino acid protein (about 52kDa), encods a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Its presence in the nucleus appears to be linked to suppression of tumor progression. The encoded protein has been shown to undergo autophosphory-lation. Very high level in colon and high levels in small intestine and prostate, and low levels in some fetal tissues. And Expressed at low level in some breast tumors, but not in normal breast. Also found in melanocytes, but not expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human PTK6 expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | PTK6 |
| Gene ID | |
| Protein Name | Protein-tyrosine kinase 6 |
| Uniprot ID |
| Molecular Weight | Theoretical: 52 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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