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Anti-PTEN Monoclonal Antibody (1G280)
(Synonyms: TEP1, PTEN1, MHAM, BZS) Copy Product Info
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Synonyms: TEP1, PTEN1, MHAM, BZS
Catalog No. TMAT-1147 Copy Product Info
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Anti-PTEN Monoclonal Antibody (1G280) is a Mouse antibody targeting PTEN. Anti-PTEN Monoclonal Antibody (1G280) can be used in WB,IF,FCM.
Anti-PTEN Monoclonal Antibody
(1G280)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Chemical Properties
Stability & Storage
| Description | Anti-PTEN Monoclonal Antibody (1G280) is a Mouse antibody targeting PTEN. Anti-PTEN Monoclonal Antibody (1G280) can be used in WB,IF,FCM. |
| Synonyms | TEP1, PTEN1, MHAM, BZS |
| Ig Type | IgG1 |
| Clone | 1G280 |
| Reactivity | Human,Mouse |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IF: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | PTEN (phosphatase and tensin homolog) was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. This protein is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of PTEN expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | PTEN |
| Gene ID | |
| Protein Name | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN |
| Uniprot ID |
| Molecular Weight | Theoretical: 54 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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