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Anti-PSMC3 Monoclonal Antibody (1K805)
(Synonyms: TBP1) Copy Product Info
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Synonyms: TBP1
Catalog No. TMAT-0878 Copy Product Info
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Anti-PSMC3 Monoclonal Antibody (1K805) is a Mouse antibody targeting PSMC3. Anti-PSMC3 Monoclonal Antibody (1K805) can be used in WB,IHC,IF,FCM.
Anti-PSMC3 Monoclonal Antibody
(1K805)
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| Description | Anti-PSMC3 Monoclonal Antibody (1K805) is a Mouse antibody targeting PSMC3. Anti-PSMC3 Monoclonal Antibody (1K805) can be used in WB,IHC,IF,FCM. |
| Synonyms | TBP1 |
| Ig Type | IgG1 |
| Clone | 1K805 |
| Reactivity | Human,Rat,Monkey |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000; IF: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases that have chaperone-like activity. This subunit may compete with PSMC2 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. A pseudogene has been identified on chromosome 9. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human *** (AA: 53-152) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | PSMC3 |
| Gene ID | |
| Protein Name | 26S proteasome regulatory subunit 6A |
| Uniprot ID |
| Molecular Weight | Theoretical: 49 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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