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Anti-PSMB8 Monoclonal Antibody (8S166)
(Synonyms: RING10, PSMB5i, MGC1491, LMP7, JMP, D6S216E, D6S216) Copy Product Info
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Synonyms: RING10, PSMB5i, MGC1491, LMP7, JMP, D6S216E, D6S216
Catalog No. TMAT-0957 Copy Product Info
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Anti-PSMB8 Monoclonal Antibody (8S166) is a Mouse antibody targeting PSMB8. Anti-PSMB8 Monoclonal Antibody (8S166) can be used in WB,IHC,IF.
Anti-PSMB8 Monoclonal Antibody
(8S166)
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Product Introduction
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Related Conjugates and Formulations
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| Description | Anti-PSMB8 Monoclonal Antibody (8S166) is a Mouse antibody targeting PSMB8. Anti-PSMB8 Monoclonal Antibody (8S166) can be used in WB,IHC,IF. |
| Synonyms | RING10, PSMB5i, MGC1491, LMP7, JMP, D6S216E, D6S216 |
| Ig Type | IgG1 |
| Clone | 8S166 |
| Reactivity | Human,Rat |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000; IF: 1/200-1/1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 3 (proteasome beta 5 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit. Two alternative transcripts encoding two isoforms have been identified; both isoforms are processed to yield the same mature subunit. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human PSMB8 expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | PSMB8 |
| Gene ID | |
| Protein Name | Proteasome subunit beta type-8 |
| Uniprot ID |
| Molecular Weight | Theoretical: 30 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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