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Anti-PSMA Monoclonal Antibody (4K969)
(Synonyms: PSM, NAALAdase, NAALAD1, mGCP, GCPII, GCP2, FOLH1, FOLH, FGCP) Copy Product Info
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Synonyms: PSM, NAALAdase, NAALAD1, mGCP, GCPII, GCP2, FOLH1, FOLH, FGCP
Catalog No. TMAT-1215 Copy Product Info
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Anti-PSMA Monoclonal Antibody (4K969) is a Mouse antibody targeting PSMA. Anti-PSMA Monoclonal Antibody (4K969) can be used in WB,FCM.
Anti-PSMA Monoclonal Antibody
(4K969)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Chemical Properties
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| Description | Anti-PSMA Monoclonal Antibody (4K969) is a Mouse antibody targeting PSMA. Anti-PSMA Monoclonal Antibody (4K969) can be used in WB,FCM. |
| Synonyms | PSM, NAALAdase, NAALAD1, mGCP, GCPII, GCP2, FOLH1, FOLH, FGCP |
| Ig Type | IgG1 |
| Clone | 4K969 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human PSMA (AA: extra 44-177) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | FOLH1 |
| Gene ID | |
| Protein Name | Glutamate carboxypeptidase 2 |
| Uniprot ID |
| Molecular Weight | Theoretical: 84.3 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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