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Anti-proBNP Antibody (1X253)
😃Good
Catalog No. TMAB-11760
Anti-proBNP Antibody (1X253) is a Mouse antibody targeting proBNP. Anti-proBNP Antibody (1X253) can be used in WB.
Anti-proBNP Antibody (1X253)
Anti-proBNP Antibody (1X253)
😃Good
Catalog No. TMAB-11760
Anti-proBNP Antibody (1X253) is a Mouse antibody targeting proBNP. Anti-proBNP Antibody (1X253) can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 200 μg | $1,058 | 7-10 days | 7-10 days | |
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-proBNP Antibody (1X253) is a Mouse antibody targeting proBNP. Anti-proBNP Antibody (1X253) can be used in WB. |
| Clone | 1X253 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Secreted. |
| Tissue Specificity | Brain and also in atria, but at much lower levels than ANP. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | PBS (pH7.4). |
| Concentration | 1mg/ml |
| Research Background | This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq]. |
| Immunogen | Recombinant Protein: human proBNP protein |
| Antigen Species | Human |
| Gene Name | NPPB |
| Gene ID | |
| Protein Name | Natriuretic peptides B |
| Uniprot ID | |
| Function | Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3. |
| Molecular Weight | Theoretical: 8.5 kDa. Actual: 10 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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