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Anti-PRKAG1 Monoclonal Antibody (2A476)
(Synonyms: AMPKG) Copy Product Info
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Synonyms: AMPKG
Catalog No. TMAT-1120 Copy Product Info
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Anti-PRKAG1 Monoclonal Antibody (2A476) is a Mouse antibody targeting PRKAG1. Anti-PRKAG1 Monoclonal Antibody (2A476) can be used in IHC,IF,FCM.
Anti-PRKAG1 Monoclonal Antibody
(2A476)
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| Description | Anti-PRKAG1 Monoclonal Antibody (2A476) is a Mouse antibody targeting PRKAG1. Anti-PRKAG1 Monoclonal Antibody (2A476) can be used in IHC,IF,FCM. |
| Synonyms | AMPKG |
| Ig Type | IgG1 |
| Clone | 2A476 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000; IF: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human PRKAG1 (AA: 230-331) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | PRKAG1 |
| Gene ID | |
| Protein Name | 5'-AMP-activated protein kinase subunit gamma-1 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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