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Anti-PRKAA2 Monoclonal Antibody (1P321)
(Synonyms: PRKAA, AMPKa2, AMPK2, AMPK) Copy Product Info
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Synonyms: PRKAA, AMPKa2, AMPK2, AMPK
Catalog No. TMAT-1121 Copy Product Info
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Anti-PRKAA2 Monoclonal Antibody (1P321) is a Mouse antibody targeting PRKAA2. Anti-PRKAA2 Monoclonal Antibody (1P321) can be used in WB,IHC,IF,FCM.
Anti-PRKAA2 Monoclonal Antibody
(1P321)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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| Description | Anti-PRKAA2 Monoclonal Antibody (1P321) is a Mouse antibody targeting PRKAA2. Anti-PRKAA2 Monoclonal Antibody (1P321) can be used in WB,IHC,IF,FCM. |
| Synonyms | PRKAA, AMPKa2, AMPK2, AMPK |
| Ig Type | IgG1 |
| Clone | 1P321 |
| Reactivity | Human,Mouse,Rat,Monkey,Rabbit |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/100-1/500; IF: 1/50-1/500; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human PRKAA2 (AA: 453-552) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | PRKAA2 |
| Gene ID | |
| Protein Name | 5'-AMP-activated protein kinase catalytic subunit alpha-2 |
| Uniprot ID |
| Molecular Weight | Theoretical: 62.3 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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