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Anti-PRF1 Monoclonal Antibody (4F930)
(Synonyms: PFP, P1, HPLH2) Copy Product Info
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Synonyms: PFP, P1, HPLH2
Catalog No. TMAT-0838 Copy Product Info
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Anti-PRF1 Monoclonal Antibody (4F930) is a Mouse antibody targeting PRF1. Anti-PRF1 Monoclonal Antibody (4F930) can be used in WB,IHC,FCM.
Anti-PRF1 Monoclonal Antibody
(4F930)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-PRF1 Monoclonal Antibody (4F930) is a Mouse antibody targeting PRF1. Anti-PRF1 Monoclonal Antibody (4F930) can be used in WB,IHC,FCM. |
| Synonyms | PFP, P1, HPLH2 |
| Ig Type | IgG1 |
| Clone | 4F930 |
| Reactivity | Human,Mouse |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a protein with structural similarities to complement component C9 that is important in immunity. This protein forms membrane pores that allow the release of granzymes and subsequent cytolysis of target cells. Whether pore formation occurs in the plasma membrane of target cells or in an endosomal membrane inside target cells is subject to debate. Mutations in this gene are associated with a variety of human disease including diabetes, multiple sclerosis, lymphomas, autoimmune lymphoproliferative syndrome (ALPS), aplastic anemia, and familial hemophagocytic lymphohistiocytosis type 2 (FHL2), a rare and lethal autosomal recessive disorder of early childhood. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human PRF1 (AA: extra 148-372) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | PRF1 |
| Gene ID | |
| Protein Name | Perforin-1 |
| Uniprot ID |
| Molecular Weight | Theoretical: 61.3 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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