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Anti-PPM1A Monoclonal Antibody (4D555)
(Synonyms: PP2C-ALPHA, PP2Calpha, PP2CA) Copy Product Info
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Synonyms: PP2C-ALPHA, PP2Calpha, PP2CA
Catalog No. TMAT-0899 Copy Product Info
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Anti-PPM1A Monoclonal Antibody (4D555) is a Mouse antibody targeting PPM1A. Anti-PPM1A Monoclonal Antibody (4D555) can be used in WB,FCM.
Anti-PPM1A Monoclonal Antibody
(4D555)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-PPM1A Monoclonal Antibody (4D555) is a Mouse antibody targeting PPM1A. Anti-PPM1A Monoclonal Antibody (4D555) can be used in WB,FCM. |
| Synonyms | PP2C-ALPHA, PP2Calpha, PP2CA |
| Ig Type | IgG1 |
| Clone | 4D555 |
| Reactivity | Human,Monkey |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase dephosphorylates, and negatively regulates the activities of, MAP kinases and MAP kinase kinases. It has been shown to inhibit the activation of p38 and JNK kinase cascades induced by environmental stresses. This phosphatase can also dephosphorylate cyclin-dependent kinases, and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to activate the expression of the tumor suppressor gene TP53/p53, which leads to G2/M cell cycle arrest and apoptosis. Three alternatively spliced transcript variants encoding distinct isoforms have been described. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human PPM1A (AA: 202-382) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | POU3F2 |
| Gene ID | |
| Protein Name | POU domain, class 3, transcription factor 2 |
| Uniprot ID |
| Molecular Weight | Theoretical: 42.4 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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