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Anti-PLOD1 Antibody (7B454)
😃Good
Catalog No. TMAB-11563
Anti-PLOD1 Antibody (7B454) is a Mouse antibody targeting PLOD1. Anti-PLOD1 Antibody (7B454) can be used in WB.
Anti-PLOD1 Antibody (7B454)
Anti-PLOD1 Antibody (7B454)
😃Good
Catalog No. TMAB-11563
Anti-PLOD1 Antibody (7B454) is a Mouse antibody targeting PLOD1. Anti-PLOD1 Antibody (7B454) can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-PLOD1 Antibody (7B454) is a Mouse antibody targeting PLOD1. Anti-PLOD1 Antibody (7B454) can be used in WB. |
| Ig Type | IgG2b,k |
| Clone | 7B454 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Rough endoplasmic reticulum membrane. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein G purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Lysyl hydroxylase is a membrane-bound homodimeric protein localized to the cisternae of the endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015] |
| Immunogen | KLH conjugated synthetic peptide: human PLOD1 |
| Antigen Species | Human |
| Gene Name | PLOD1 |
| Gene ID | |
| Protein Name | Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 |
| Uniprot ID | |
| Function | Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links. |
| Molecular Weight | Theoretical: 33 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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