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Anti-PLCG1 Monoclonal Antibody (7T655)
(Synonyms: PLC-II, PLCgamma1, PLC148, PLC1, NCKAP3) Copy Product Info
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Synonyms: PLC-II, PLCgamma1, PLC148, PLC1, NCKAP3
Catalog No. TMAT-0886 Copy Product Info
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Anti-PLCG1 Monoclonal Antibody (7T655) is a Mouse antibody targeting PLCG1. Anti-PLCG1 Monoclonal Antibody (7T655) can be used in WB,IHC,IF,FCM.
Anti-PLCG1 Monoclonal Antibody
(7T655)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Chemical Properties
Stability & Storage
| Description | Anti-PLCG1 Monoclonal Antibody (7T655) is a Mouse antibody targeting PLCG1. Anti-PLCG1 Monoclonal Antibody (7T655) can be used in WB,IHC,IF,FCM. |
| Synonyms | PLC-II, PLCgamma1, PLC148, PLC1, NCKAP3 |
| Ig Type | IgG1 |
| Clone | 7T655 |
| Reactivity | Human,Mouse |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000; IF: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human PLCG1 (AA: 1192-1291) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | PLCG1 |
| Gene ID | |
| Protein Name | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 |
| Uniprot ID |
| Molecular Weight | Theoretical: 148.5 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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