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Anti-Pkd1 Monoclonal Antibody (5H393)
(Synonyms: PC1, Mflj00285) Copy Product Info
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Synonyms: PC1, Mflj00285
Catalog No. TMAT-0568 Copy Product Info
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Anti-Pkd1 Monoclonal Antibody (5H393) is a Rat antibody targeting Pkd1. Anti-Pkd1 Monoclonal Antibody (5H393) can be used in FCM.
Anti-Pkd1 Monoclonal Antibody
(5H393)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-Pkd1 Monoclonal Antibody (5H393) is a Rat antibody targeting Pkd1. Anti-Pkd1 Monoclonal Antibody (5H393) can be used in FCM. |
| Synonyms | PC1, Mflj00285 |
| Ig Type | gG1 |
| Clone | 5H393 |
| Reactivity | Human |
| Application | |
| Recommended Dose | FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Rat |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | Involved in renal tubulogenesis. Involved in fluid-flow mechanosensation by the primary cilium in renal epithelium. Acts as a regulator of cilium length, together with PKD2. The dynamic control of cilium length is essential in the regulation of mechanotransductive signaling. The cilium length response creates a negative feedback loop whereby fluid shear-mediated deflection of the primary cilium, which decreases intracellular cAMP, leads to cilium shortening and thus decreases flow-induced signaling. May be an ion-channel regulator. Involved in adhesive protein-protein and protein-carbohydrate. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of mouse PKD1 (AA: 3682-3873) expressed in E. Coli. |
| Antigen Species | Mouse |
| Gene Name | Pkd1 |
| Gene ID | |
| Protein Name | Polycystin-1 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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